Results 11 to 20 of about 59,761 (296)

Selective serotonin reuptake inhibitors [PDF]

open access: yesBMJ, 2004
The increasing use of antidepressants—particularly the selective serotonin reuptake inhibitors (SSRIs)—might be grounds for optimism because it might indicate that one of the great health problems of our age is increasingly being recognised and treated. Instead SSRIs have become embroiled in controversy over both their effectiveness and safety. As well
Geddes J., CIPRIANI, Andrea
  +6 more sources

Selective serotonin reuptake inhibitors pathway [PDF]

open access: yesPharmacogenetics and Genomics, 2009
Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter that influences multiple processes, including autonomic function, motor activity, hormone secretion, cognition, and complex processes associated with affection, emotion, and reward [1]. In the terminal axon of the serotonergic neuron, free tryptophan (TRP) is converted to 5-HT [2].
Katrin, Sangkuhl   +2 more
openaire   +2 more sources

Thrombocytopenia due to escitalopram use – A rare case report at the emergency department

open access: yesIraqi Journal of Hematology, 2021
Selective serotonin reuptake inhibitors are commonly used in the treatment of many psychiatric diseases today. Their common side effects consist of gastrointestinal side effects, sexual dysfunction, headache, insomnia, and sedation, whereas hematological
Cihan Bedel, Mustafa Korkut
doaj   +1 more source

Selective serotonin reuptake inhibitors in the treatment of generalized anxiety disorder [PDF]

open access: yes, 2002
Selective serotonin reuptake inhibitors have proven efficacy in the treatment of panic disorder, obsessive–compulsive disorder, post-traumatic stress disorder and social anxiety disorder.
Allgulander C   +41 more
core   +1 more source

Use of antidepressants near delivery and risk of postpartum hemorrhage: cohort study of low income women in the United States [PDF]

open access: yes, 2014
Objective: To determine whether use of serotonin or non-serotonin reuptake inhibitors near to delivery is associated with postpartum hemorrhage. Design Cohort study. Setting 2000-07 nationwide Medicaid data (Medicaid Analytic eXtract). Population 106 000
Achtyes, Eric D   +7 more
core   +1 more source

Milnacipran Inhibits Itch-Related Responses in Mice Through the Enhancement of Noradrenergic Transmission in the Spinal Cord

open access: yesJournal of Pharmacological Sciences, 2013
We investigated whether milnacipran, a serotonin–noradrenaline reuptake inhibitor, exhibits an antipruritic effect through the spinal action in mice.
Tsugunobu Andoh   +2 more
doaj   +1 more source

Fluoxetine: a case history of its discovery and preclinical development [PDF]

open access: yes, 2014
Introduction: Depression is a multifactorial mood disorder with a high prevalence worldwide. Until now, treatments for depression have focused on the inhibition of monoaminergic reuptake sites, which augment the bioavailability of monoamines in the CNS ...
Bel N   +20 more
core   +2 more sources

Preclinical discovery of duloxetine for the treatment of depression [PDF]

open access: yes, 2012
Introduction: Affective disorders, including major depressive disorder (MDD), are among the most severely disabling mental disorders, and in many cases areIntroduction: Affective disorders, including major depressive disorder (MDD), are among the most ...
Berrocoso Domínguez, Esther María   +4 more
core   +2 more sources

Antidepressants in pregnancy and breastfeeding [PDF]

open access: yes, 2007
Copyright © 2007 Australian Prescriber Reproduced with permission from Australian Prescriber The document attached has been archived with permission from the publisher/copyright holder.Maternal depression and anxiety during pregnancy and the early years ...
Sved-Williams, A.
core   +1 more source

Selective Serotonin Reuptake Inhibitors

open access: yes, 2017
Selective serotonin reuptake inhibitors (SSRIs) are used primarily for treatment of depression and anxiety. Their effectiveness in pain management is limited and inconsistent.
Robert M. Chow, Mohammed Issa
  +4 more sources

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