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Selective serotonin reuptake inhibitors

Nurse Prescribing, 2010
Selective serotonin reuptake inhibitors (SSRIs) are used widely for the treatment of depression and anxiety disorders, and different SSRIs have different licence indications. They prevent the reuptake of serotonin in the synapse between nerve cells; they should be used with caution in children and adolescents owing to the possible side-effect of an ...
Michael M. Morgan   +199 more
openaire   +2 more sources

Selective Serotonin Reuptake Inhibitor Exposure

Topics in Companion Animal Medicine, 2013
Many antidepressants inhibit serotonin or norepinephrine reuptake or both to achieve their clinical effect. The selective serotonin reuptake inhibitor class of antidepressants (SSRIs) includes citalopram, escitalopram (active enantiomer of citalopram), fluoxetine, fluvoxamine, paroxetine, and sertraline.
Kevin T, Fitzgerald, Alvin C, Bronstein
openaire   +2 more sources

Selective Serotonin Reuptake Inhibitors

2018
The first antidepressants were created by chance but brought the idea that central serotonin agonism produced an antidepressant effect. SSRIs were the first class of psychotropic medications to be rationally designed, meaning that researchers intended to utilize a specific mechanism of action while avoiding adverse effects.
Dee, Lochmann, Tara, Richardson
openaire   +2 more sources

Selective Serotonin Reuptake Inhibitors

2011
Selective serotonin reuptake inhibitors (SSRIs) are one of the newer classes of antidepressants. Since their introduction in the United States, they have been greatly used and accepted in the psychiatric field (1). SSRIs presently available in the United States include fluoxetine, paroxetine, sertraline, fluvoxamine, and citalopram.
JoAnn T. Tschanz, Katherine Treiber
openaire   +2 more sources

Selective Serotonin Reuptake Inhibitor-Induced Serotonin Syndrome

Journal of Clinical Psychopharmacology, 1997
The selective pharmacology of the selective serotonin reuptake inhibitors (SSRIs) results in a lower potential for pharmacodynamic drug interactions relative to other antidepressants such as the tricyclic antidepressants (TCAs) and monoamine oxidase inhibitors (MAOIs). However, the SSRIs have been implicated in the development of the serotonin syndrome-
R, Lane, D, Baldwin
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Selective Serotonin Reuptake Inhibitors in Pregnancy

Current Medicinal Chemistry, 2012
The use of antidepressant drugs, such as selective serotonin reuptake inhibitors (SSRIs), during pregnancy is rapidly increasing. To date, the effects of SSRI on pregnant women and fetuses are controversial and still a matter of debate. Although a number of studies have shown that these antidepressants are not teratogenic, some of them have reported an
V, Bellissima   +3 more
openaire   +2 more sources

Selective serotonin reuptake inhibitor-induced akathisia

Journal of the American Pharmacists Association, 2009
To review available information in the literature about akathisia (inner restlessness) caused by the selective serotonin reuptake inhibitors (SSRIs).Databases searched included Medline, PsychInfo, the International Pharmaceutical Abstracts, and Google Scholar. Search terms included drug-induced akathisia, psychomotor agitation, drug-induced side effect,
Lindsey P, Koliscak, Eugene H, Makela
openaire   +2 more sources

Clastogenicity of selective serotonin-reuptake inhibitors

Mutation Research/Genetic Toxicology and Environmental Mutagenesis, 2004
Selective serotonin-reuptake inhibitors (SSRIs) are used in the treatment of various forms of psychiatric disorders. Preclinical studies in laboratory animals have indicated that SSRIs were not genotoxic, but clear results from in vitro testing of SSRIs in a human cell system are currently scarce.
Gokay, Bozkurt   +8 more
openaire   +2 more sources

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