Results 51 to 60 of about 59,761 (296)

Pencarian Hubungan Adverse Event pada Obat Penenang dengan Apriori

Jurnal CoreIT: Jurnal Hasil Penelitian Ilmu Komputer dan Teknologi Informasi, 2016
SSRI (Selective Serotonin Reuptake Inhibitor) merupakan salah satu jenis obat antidepresan yang dikonsumsi penderita gangguan kecemasan dan gangguan panik dan juga paling banyak digunakan diseluruh dunia, karena diyakini mengurangi resiko bunuh diri ...
Meilinda Heriza, Muhammad Fikri, Lestari Handayani   +2 more
doaj   +1 more source

Reversible Hemifacial Spasm after Starting Escitalopram

Case Reports in Neurology, 2020
This is a case of a patient who developed hemifacial spasm after he was started on escitalopram. His symptoms got worse after the dose was increased. The spasm resolved after the medication was stopped gradually.
Mazen Abdulrahaman Basheikh
doaj   +1 more source

Chirality of Modern Antidepressants: An Overview [PDF]

Advanced Pharmaceutical Bulletin, 2017
The majority of modern antidepressants (selective serotonin reuptake inhibitors and selective serotonin and norepinephrine reuptake inhibitors) have one or two centers of asymmetry in their structure; resulting in the formation of enantiomers which may ...
Monica Budău, Gabriel Hancu, Aura Rusu, Melania Cârcu-Dobrin, Daniela Lucia Muntean   +4 more
doaj   +1 more source

A functional variant in the serotonin receptor 7 gene (HTR7), rs7905446, is associated with good response to SSRIs in bipolar and unipolar depression. [PDF]

, 2020
Predicting antidepressant response has been a clinical challenge for mood disorder. Although several genome-wide association studies have suggested a number of genetic variants to be associated with antidepressant response, the sample sizes are small and
Aitchison, Katherine J, Binder, Elisabeth B, Carrillo-Roa, Tania, Cattaneo, Annamaria, DeModena, Anna, Henigsberg, Neven, Kelsoe, John R, Leckband, Susan G, Liu, Jia Jia, McCarthy, Michael, Mors, Ole, Ren, Hongyan, Rietschel, Marcella, Shekhtman, Tatyana, Wei, Ya Bin   +14 more
core   +2 more sources

Functional Analysis of Ligand‐Gated Chloride Channels in a Cnidarian Sheds Light on the Evolution of Inhibitory Signaling

Advanced Science, EarlyView.
We uncover a large variety of putative inhibitory ligand‐gated ion channels (LGICs) in the phylum Cnidaria, the sister group to all bilaterian animals. Phylogenetic analysis suggests a complex evolutionary history of inhibitory LGICs with diverse neurotransmitter ligands.
Abhilasha Ojha, Linda Kloss, Juan D. Montenegro, Simone Albani, Audrey Ortega‐Ramírez, Mihaela Raycheva, Sylvia Joussen, Sabrina Kaul, Michèle Bachmann, Lisa Huf, Günther Schmalzing, Alison G. Cole, Ulrich Technau, Stefan Gründer   +13 more
wiley   +1 more source

Effect of glibenclamide on antinociceptive effects of antidepressants of different classes

Clinics, 2011
OBJECTIVES: The purpose of this work was to determine whether the intraperitoneal administration of glibenclamide as a K ATP channel blocker could have an effect on the antinociceptive effects of antidepressants with different mechanisms of action ...
Valiollah Hajhashemi, Bahareh Amin
doaj   +1 more source

A Novel Biotinylated Homotryptamine Derivative for Quantum Dot Imaging of Serotonin Transporter in Live Cells

Frontiers in Cellular Neuroscience, 2021
The serotonin transporter (SERT) is the primary target for selective serotonin reuptake inhibitor (SSRI) antidepressants that are thought to exert their therapeutic effects by increasing the synaptic concentration of serotonin.
Ian D. Tomlinson, Oleg Kovtun, Ruben Torres, Ruben Torres, Laurel G. Bellocchio, Travis Josephs, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal, Sandra J. Rosenthal   +11 more
doaj   +1 more source

Adjunctive quetiapine for serotonin reuptake inhibitor-resistant obsessive-compulsive disorder: A meta-analysis of randomised controlled treatment trials [PDF]

, 2006
Small studies have shown positive effects from adding a variety of antipsychotic agents in patients with obsessive–compulsive disorder who are unresponsive to treatment with serotonin reuptake inhibitors. The evidence, however, is contradictory.
Carey, P, Denys, D, Fineberg, N, Premkumar, P, Seedat, S, Sivakumaran, T, Stein, DJ, Vythilingum, B, Westenberg, H   +8 more
core   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Adverse Childhood Experiences in Autistic and Neurotypical Girls

Autism Research, EarlyView.
ABSTRACT Adverse childhood experiences (ACEs) are potentially traumatic, life‐altering events that occur in childhood with long‐term negative physical and/or mental health outcomes. Previous research, while limited and largely focused on males, suggests children with autism spectrum disorder (ASD) are at higher risk of experiencing ACEs than typically ...
Jon Ebert, Rachael A. Muscatello, Trey McGonigle, Simon Vandekar, Blythe A. Corbett   +4 more
wiley   +1 more source