Results 221 to 230 of about 85,863 (303)

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 6, Page 1574-1583, June 2026.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt   +8 more
wiley   +1 more source

Selective serotonin reuptake inhibitors induce cardiac toxicity through dysfunction of mitochondria and sarcomeres. [PDF]

open access: yesCommun Biol
Shen Y   +9 more
europepmc   +1 more source

Serum Amyloid β Oligomer May Predict Treatment Response in Middle‐Aged and Late‐Life Patients With Depression

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
After 4 weeks of antidepressant treatment, patients with serum amyloid β oligomers showed a significantly lower treatment response compared with those without Aβ oligomers among middle‐aged and late‐life patients with major depressive disorder. ABSTRACT Aim Late‐life patients with depression are reportedly less responsive to antidepressant treatment ...
Kentaro Shimizu   +4 more
wiley   +1 more source

Akathisia Induced by Metoclopramide in a Pregnant Woman With Nausea and Vomiting: A Case Report

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
This case report describes a patient who was hospitalized at 33 weeks of gestation and diagnosed with metoclopramide‐induced akathisia. Although the akathisia symptoms resolved 3 days after discontinuation of metoclopramide, a possible interaction with dextromethorphan, which the patient had been orally administering prior to hospitalization, cannot be
Ryohei Nakamura   +6 more
wiley   +1 more source

Efficacy and Tolerability of Vortioxetine Versus Selective Serotonin Reuptake Inhibitors for Late-Life Depression: A Post-hoc Analysis of the VESPA Study. [PDF]

open access: yesDrugs Aging
Bartoli F   +26 more
europepmc   +1 more source

Glutathione‐Related Metabolite Levels and Enzyme Activities in Depression: A Systematic Review and Meta‐Analysis

open access: yesNeuropsychopharmacology Reports, Volume 46, Issue 2, June 2026.
We conducted a systematic review and meta‐analysis to compare the levels of glutathione‐related metabolites. Our meta‐analysis indicated significantly decreased activity of glutathione‐peroxidase in patients with depression compared with healthy controls, while the levels of glutathione and glutathione reductase were not significantly different between
Takahide Etani   +16 more
wiley   +1 more source

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