Results 101 to 110 of about 1,782,143 (350)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
ChemElectroChemElectrocatalytic selectivity is generally explained in terms of atomic‐scale properties, i.e., active sites, overlooking the impact of macroscopic electrode geometry and structure, which affect the macroscopic mass transport.
Ali Raza Khan +9 more
doaj +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Inhibitory Antibodies Designed for Matrix Metalloproteinase Modulation
Molecules, 2019 The family of matrix metalloproteinases (MMPs) consists of a set of biological targets that are involved in a multitude of severe pathogenic events such as different forms of cancers or arthritis.
Thomas Fischer, Rainer Riedl
doaj +1 more source
Residual stress via the contour method in compact tension specimens produced via selective laser melting [PDF]
, 2014 Bey Vrancken +3 more
openalex +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Aid Selectivity According to Augmented Criteria [PDF]
A dominant trend in the literature maintains that donor assistance should be targeted to poor countries with sound institutions and policies. In this context, donor selectivity refers to what extent aid is allocated according to the principles of this ...
Jacky AMPROU +2 more
core +3 more sources
Toxicity of organic supplies for the egg parasitoid Telenomus podisi [PDF]
Ciência Rural, 2014 Toxicity (dosage per hectare) of: 1) Baculovirus anticarsia 140x109 cpi; 2) Bacillus thuringiensis 16.8g; 3) Azadirachtin-A, azadirachtin-B, nimbina and salamina 9.6 ppm; 4) Rotenoids 4 liters; 5) Nitrogen 1.3%, phosphorus 3.0% and total organic carbon 8.
Débora Mello da Silva +1 more
doaj
Ciência e Agrotecnologia, 2006 O controle do bicho-mineiro-do-cafeeiro Leucoptera coffeella (Guérin-Mèneville & Perrottet, 1842) é realizado por meio de inseticidas de amplo espectro de ação, capazes de causar desequilíbrios biológicos, sendo importante a busca por produtos que ...
José Marcos Angélico de Mendonça +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source