Results 1 to 10 of about 18,634 (212)

Selenomethionine as a dual-mechanism ferroptosis inhibitor: selenium-supply-driven GPX4 biosynthesis beyond transsulfuration and reductive-capacity-mediated ROS scavenging independent of GPX4 activity [PDF]

Cell Death and Disease
Ferroptosis is an iron-dependent form of nonapoptotic cell death driven by lipid peroxidation. The selenium-dependent glutathione peroxidase 4 (GPX4) serves as the central regulator of ferroptosis through enzymatic reduction of phospholipid ...
Chaoyi Xia, Xue Sun, Junyi Shao, Jingshu Min, Chong Wei, Feiyang Zhao, Caiyun Fu, Qiang Zhang   +7 more
doaj   +2 more sources

Selenomethionine metabolism and its toxicity in yeast

Biomolecular Concepts, 2013
The importance of selenium for organisms can be explained by its existence as selenocysteine in the catalytic centers of glutathione peroxidase and thioredoxin reductase. Another selenoamino acid, selenomethionine, is the major form of selenium in foods,
Kitajima Toshihiko, Chiba Yasunori
doaj   +3 more sources

Relative bioavailability of selenium yeast, selenomethionine, hydroxyl-selenomethionine and nano-selenium for broilers. [PDF]

Front Vet Sci
Selenium (Se) is an essential trace element for humans and animals. Development and application of new forms of Se sources with lower toxicity and higher bioavailability has been attracting more attention. However, the bioavailabilities of Se from several new Se sources for broilers remain unclear.
Liu G, Cao S, Huang L, Lin X, Sun Z, Lin G, Zhang L, Lu L, Luo X, Liao X.   +9 more
europepmc   +3 more sources

Administration of selenomethionine in combination with serine benefits diabetes via gut microbiota

Frontiers in Microbiology, 2022
Either selenium or serine could modulate glucose homeostasis, however, whether there are synergistic effects of selenium with serine on diabetes remains to be unknown.
Xiaoyan Cui, Jingqing Chen, Jingqing Chen, Yuexi Yang   +3 more
doaj   +1 more source

Intestinal barrier dysfunction induced by ammonia exposure in pigs in vivo and in vitro: The protective role of L-selenomethionine

Ecotoxicology and Environmental Safety, 2022
Ammonia has been reported to have a variety of toxicity to aquatic animals, farm animals and humans. However, its potential toxicity on the intestines remains unknown. L-selenomethionine is one of the important organic selenium sources.
Xinxin Zhang, Anqi Wang, Ying Chen, Jun Bao, Houjuan Xing   +4 more
doaj   +1 more source

Influence of selenomethionine and omega-3 fatty acid on serum mineral profile and nutrient utilization of broiler chicken [PDF]

Veterinary World, 2015
Aim: This study was conducted to investigate the effect of selenomethionine and omega-3 fatty acid on serum mineral profile and nutrient utilization of broiler chicken.
Pankaj Kumar, S. P. Tiwari, Tarini Sahu , Surendra Kumar Naik   +3 more
doaj   +1 more source

Isolation, Purification and Crystallization of Restriction Enzyme Bsa I and Its Preparation of Seleno-derived Derivatives

Shipin gongye ke-ji, 2023
Objective: To screen and optimize the method for preparing three-dimensional structural samples of restriction endonuclease Bsa I. Methods: In this study, the Escherichia coli expression system was employed to express the Bsa I protein and its ...
Hai ZHU, Mengze ZHENG, Weiwei JIA, Qian ZHOU, Shuai TAN, Ziang LIU, Chuanzhi ZHANG, Weiling WANG, Tingting LI   +8 more
doaj   +1 more source

Selenium alleviates porcine nephrotoxicity of ochratoxin A by improving selenoenzyme expression in vitro. [PDF]

PLoS ONE, 2015
Ochratoxin A (OTA), a mycotoxin, is a potent nephrotoxin in humans and animals. Selenium (Se) is an essential micronutrient for humans and animals, and plays a key role in antioxidant defense.
Fang Gan, Hongxia Xue, Yu Huang, Cuiling Pan, Kehe Huang   +4 more
doaj   +1 more source

Modification of the terms of authorisation of zinc‐l‐selenomethionine as a feed additive for all animal species (Zinpro Animal Nutrition (Europe), Inc.)

EFSA Journal, 2023
Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a new preparation of zinc‐l‐selenomethionine, with selenium content of 4%, as a nutritional feed additive for all animal ...
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Vasileios Bampidis, Giovanna Azimonti, Maria de Lourdes Bastos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Maryline Kouba, Marta López‐Alonso, Secundino López Puente, Francesca Marcon, Baltasar Mayo, Alena Pechová, Mariana Petkova, Fernando Ramos, Roberto Edoardo Villa, Ruud Woutersen, Jaume Galobart, Matteo Lorenzo Innocenti, Maria Vittoria Vettori, Anita Radovnikovic   +20 more
doaj   +1 more source

The time pattern of selenomethionine administration in preventing free radicals due to exposure to electric cigarette smoke

Journal of Public Health Research, 2021
Background: Most people believe that electric cigarettes have no negative effect on health,  which causes them to use it more. However, exposure to the smoke from these cigarettes is bad for the health and causes cell damage.
Rivan Virlando Suryadinata, Bambang Wirjatmadi, Amelia Lorensia   +2 more
doaj   +1 more source