Results 31 to 40 of about 13,403 (164)

Selenomethionine Improves Mitochondrial Function by Upregulating Mitochondrial Selenoprotein in a Model of Alzheimer’s Disease

open access: yesFrontiers in Aging Neuroscience, 2021
Alzheimer’s disease (AD), the most common neurodegenerative disease in elderly humans, is pathologically characterized by amyloid plaques and neurofibrillary tangles.
Chen Chen   +10 more
doaj   +1 more source

Selenomethionine inhibits ultraviolet radiation-induced p53 transactivation

open access: yes, 2006
Background: Ultraviolet (UV) radiation damages the cellular DNA of skin cells. In response, wild-type p53 protein accumulates in irradiated cells and the stabilized and transactivated protein can then induce genes involved in cell cycle arrest in G1, or ...
Traynor, Nicola J.   +7 more
core   +1 more source

The mechanism of action of the anticancer effects of selenomethionine on colon cancer

open access: yes, 2001
Selenomethionine, an organic derivative of selenium, has been found to be the predominate selenium component of the dietary cancer chemopreventive agent selenized yeast that has been shown to decrease the incidence and mortality rate of lung, colon, and ...
Baines, Antonio Thomas
core   +4 more sources

Effect of Trace Element Selenium on the Intestinal Microbial Community in Nude Mice with Colorectal Cancer

open access: yesMicroorganisms
Colorectal cancer (CRC) is the third most common cancer worldwide. The role of intestinal microbiota in carcinogenesis has also become an important research topic, and CRC is closely related to the intestinal microbiota.
Yintong Su   +4 more
doaj   +1 more source

Methionine Changes in Bacteriorhodopsin Detected by FTIR and Cell-Free Selenomethionine Substitution [PDF]

open access: yes, 2003
Bacteriorhodopsin (BR) is an integral membrane protein, which functions as a light-driven proton pump in Halobacterium salinarum. We report evidence that one or more methionine residues undergo a structural change during the BR→M portion of the BR ...
Jerzy Olejnik   +7 more
core   +1 more source

Fontes orgânicas e inorgânicas de selênio na nutrição de vacas leiteiras: digestão, absorção, metabolismo e exigências Organic and inorganic sources of selenium in the nutrition of dairy cows: digestion, absorption, metabolism and requirements

open access: yesCiência Rural, 2007
A suplementação de bovinos leiteiros com selênio é feita tanto em sua forma orgânica como inorgânica. Nas plantas, o Se é incorporado aleatoriamente na sua forma orgânica e encontra-se como análogo de aminoácidos sulfurados, ou seja, selenometionina e ...
Martin Gierus
doaj   +1 more source

Selenomethionine Antagonized microRNAs Involved in Apoptosis of Rat Articular Cartilage Induced by T-2 Toxin

open access: yesToxins, 2023
T-2 toxin and selenium deficiency are considered important etiologies of Kashin–Beck disease (KBD), although the exact mechanism is still unclear. To identify differentially expressed microRNAs (DE-miRNAs) in the articular cartilage of rats exposed to T ...
Fangfang Yu   +7 more
doaj   +1 more source

Data of radiation damage on selenomethionine-substituted single-domain substrate-binding protein

open access: yesData in Brief
Radiation damage is an inherent issue in X-ray crystallography. It not only damages macromolecular crystals, which lowers the quality of the diffraction intensity, but results in inaccurate structural information.
Ki Hyun Nam
doaj   +1 more source

Effects of different sources of selenium supplementation on antioxidant indices, biochemical parameters, thyroid hormones and Se status in transition cows

open access: yesActa Scientiarum: Animal Sciences, 2019
The aim of this study was to determine the effects of supplementing close-up and fresh dairy cows’ diets with sodium selenite or organic sources of selenium (Se) on the serum biochemical parameters and antioxidant indicators and Se status.
Mohsen Khalili   +4 more
doaj   +1 more source

Selenomethionine Regulates the Arachidonic Acid Metabolism‐Ferroptosis‐Inflammation Axis to Ameliorate Colitis

open access: yesAnimal Research and One Health, EarlyView.
Selenomethionine can ameliorate arachidonic acid‐induced colonic injury through synergistic mechanisms, including alleviating inflammatory responses, improving barrier integrity, enhancing antioxidant capacity by upregulating selenoprotein expression, selectively regulating AA metabolism to reduce pro‐inflammatory oxylipins and promote the production ...
Huihui Tian   +8 more
wiley   +1 more source

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