Results 101 to 110 of about 205,586 (228)
Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells
FEBS Open Bio, EarlyView.UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca +6 more
wiley +1 more source
Synthesis and Characterization of Tungstite (WO3.H2O) Nanoleaves and Nanoribbons
, 2014 An environmentally benign method capable of producing large quantities of materials was used to synthesize tungstite (WO3.H2O) leaf-shaped nanoplatelets (LNPs) and nanoribbons (NRs).
Ahmadi, Majid, Guinel, Maxime J-F
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
AggregateZwitterionic hydrogels have attracted considerable attention as advanced biomaterials. However, the fabrication of traditional zwitterionic hydrogels typically relies on harsh polymerization conditions, and their backbone structures are non‐biodegradable.
Xiaohui Li +11 more
doaj +1 more source
Do self-ligating brackets favor greater bacterial aggregation?
Brazilian Journal of Oral Sciences, 2015 Aim: To verify the hypothesis that self-ligating brackets favor greater aggregation of microorganisms when compared with conventional brackets. Methods: Four types of self-ligating metal brackets were evaluated.
Matheus M. Pithon +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Non-Rotating Convective Self-Aggregation in a Limited Area AGCM [PDF]
We present non-rotating simulations with the Goddard Earth Observing System (GEOS) atmospheric general circulation model (AGCM) in a square limited area domain over uniform sea surface temperature.
Arnold, Nathan P., Putman, William M.
core +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
FEBS Open Bio, EarlyView.Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source
Advanced ScienceMicroalgae–bacteria symbiosis system is significant for sustainable and low‐carbon wastewater treatment, with self‐aggregation being key to its stable operation and effective pollutant removal.
Luyu Zhang +7 more
doaj +1 more source