Results 51 to 60 of about 4,752,657 (192)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Novel encapsulation technologies for small size-scale self-healing applications [PDF]
, 2011 Self-healing technology offers an autonomic route to repairing damage in advanced polymers to extend their lifetime. A variety of self-healing systems have been developed for mechanical self-healing, protective coatings, and electronic self-healing ...
Jackson, Aaron C.
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Advanced Materials InterfacesSuperhydrophobic surfaces have important application prospects and value in industry and daily life. However, the practical application of superhydrophobic surfaces is severely hindered by their poor durability.
Xue Bai, Wenjin Chen, Pei Wang
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Advanced ScienceHydrogel‐based zinc‐air batteries (ZABs) are promising flexible rechargeable batteries. However, the practical application of hydrogel‐based ZABs is limited by their short service life, narrow operating temperature range, and repair difficulty. Herein, a
Hongli Li +3 more
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Water‐Triggered Reconfigurable Glycerogels for Sustainable All‐Gel Supercapacitors
Advanced ScienceThe polymeric structures of synthetic gels are typically static, which makes them damage‐prone and nonrecyclable. Inspired by the dynamic reconfigurability of biological tissues, which eliminate old/damaged cells and regenerate new ones via biological ...
Md. Tariful Islam Mredha +3 more
doaj +1 more source
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Self-healing materials and multinozzle printheads with embedded microvascular networks [PDF]
, 2011 Microvascular networks are pervasive in biological systems, assisting in the repair of tissue damage, regulation of temperature, and efficient distribution of nutrients.
Hansen, Christopher J.
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