Results 71 to 80 of about 269,140 (232)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Evaluation of the performance of self-healing concrete at small and large scale under laboratory conditions [PDF]

open access: yes, 2017
HEALCON is an EU-FP7 project which aims to develop self-healing concrete to create durable and sustainable concrete structures. While during the first years of the project the self-healing materials (including the healing agents and suitable ...
Branco, Vanda   +10 more
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Smart Materials to Empowering Perovskite Solar Cells with Self‐Healing Capability

open access: yesSmall Structures
Inspired by nature, intelligent self‐healing materials have recently been exploited also in the field of photovoltaics to mimic natural systems achieving self‐repairing.
Riccardo Pallotta   +3 more
doaj   +1 more source

Non-destructive testing techniques for the observation of healing effects in cementitious materials: an introduction [PDF]

open access: yes, 2013
To develop an appropriate method of self-healing for cementitious materials including the right composition and amount of suitable healing agents it is required to investigate the healing efficiency for certain material mixtures.
De Belie, Nele   +2 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Particle coating using foams and bubbles : a thesis presented in partial fulfilment of the requirements for the degree of Doctor of Philosophy in Chemical and Bioprocess Engineering at Massey University, Palmerston North, New Zealand [PDF]

open access: yes, 2017
This thesis investigates powder coating using foams or bubbles. The work initially started on foams. Wettability studies first showed that foams can be used to coat powders. Research then focussed on the fundamental unit of foams, the bubble.
Singh, Shakti
core  

Adaptive Fault Detection exploiting Redundancy with Uncertainties in Space and Time

open access: yes, 2019
The Internet of Things (IoT) connects millions of devices of different cyber-physical systems (CPSs) providing the CPSs additional (implicit) redundancy during runtime.
Bartocci, Ezio   +3 more
core   +2 more sources

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