Results 81 to 90 of about 4,752,657 (192)
Exploring Self‐Repair Capabilities of ATSP Vitrimers for Crack Mitigation in Aerospace Applications
Macromolecular Materials and EngineeringVitrimers, although categorized as thermosetting polymers, differ from traditional ones in that their thermally induced crosslinks undergo reconfiguration through covalent bond exchanges in response to thermal stimuli.
Ajinkya Raut +3 more
doaj +1 more source
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
Mechanical characterization and self-healing in synthetic vascularized materials [PDF]
, 2011 Inspired by natural healing processes, a variety of synthetic self-healing materials have been developed that mechanically recover from structural damage autonomously.
Hamilton, Andrew R.
core
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Healing for Our Stolen Generations: sharing our stories
, 2016 Executive summary This report is a review of the first two years of projects funded under the Healing Foundation’s Stolen Generations Initiative 2013-2015.
Healing Foundation
core
Concrete self-healing performance using surface roughness parameters: Metrological approach [PDF]
Traditional test methods for evaluating concrete self-healing performance, such as scanning electron microscopy, ultrasonic waves including velocity pulse and emissions and x-ray imaging have limited accuracy resulting from the damages during the sample ...
Giustozzi, Filippo +4 more
core +1 more source
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Self-healing of high temperature cured epoxy and composites [PDF]
, 2012 The use of structural fiber-reinforced polymeric composites and epoxy adhesives in aircraft, ships, vehicles, and wind turbine blades has increased markedly in the past decades.
Jin, Henghua
core