Results 51 to 60 of about 6,364,062 (240)

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Study on the relationship between self⁃care self⁃efficacy and self⁃perceived burden among patients with lung cancer undergoing chemotherapy

open access: yesHuli yanjiu, 2020
ObjectiveTo investigate the status of self⁃perceived burden and self⁃care self⁃efficacy in patients with lung cancer undergoing chemotherapy,and to explore the influence of self⁃care self⁃efficacy on self⁃perceived burden.MethodsTotally 140 patients with
XIAO Miao, YI Yuli, WEI Binbin
doaj  

Relationship between self-perceived burden and quality of life among stroke patients

open access: yes, 2022
Introduction:Although there is evidence that self-perceived burden is associated with quality of life, and that self-perceived burden may influence the level of quality of life, evidence for any association in stroke patients is weak.
Wu, Yuxue
core  

Self-perceived outcomes by season.

open access: yes, 2021
Self-perceived outcomes by season.
Sandra C. Webber (11624690)   +2 more
core   +1 more source

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Perceived Burden and Healthy Lifestyle Behavior in Family Caregivers of the Persons with Disabilities in Bukhara [PDF]

open access: yes
Objective: Family caregiving is a common tradition to Uzbekistan. The responsibilities of caring for a person with disabilities may cause caregivers to develop risky health behaviors and become a burden for them.
Nurhayat KORKMAZ, Hülya YÜCEL
core   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Health self-perception by dementia family caregivers: sociodemographic and clinical factors

open access: yesArquivos de Neuro-Psiquiatria, 2011
Caring for a demented family member has been associated with burden. Studies concerning health self-perception of family caregivers are still scarce. OBJECTIVE: To investigate caregivers perceived health and to look into relationships with patients and ...
Letice Ericeira Valente   +9 more
doaj   +1 more source

Quality of life among older people with poor functioning. The influence of perceived control over life [PDF]

open access: yes, 2007
Objective: to investigate the apparently incongruous coupling of poor physical functioning with high QoL.Study design and setting: face-to-face interview survey of random sample of 999 people aged 65+ across Britain.Results: twenty-one per cent of ...
Morris, R   +7 more
core   +1 more source

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