Results 221 to 230 of about 979,898 (268)

ACTH self-administration in rats

Pharmacology Biochemistry and Behavior, 1979
The ability of rats to learn a lever pressing response reinforced by a contingent intravenous delivery of ACTH 1--24 and 4--10, was investigated. About 60% of the rats tested learned to press the lever for the two analogues that were infused at a rate of 2.08 microgram per second via a chronically implanted intrajugular catheter.
M, Jouhaneau-Bowers, J, Le Magnen
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Methamphetamine self-administration in the cat

Psychopharmacologia, 1976
A procedure for studing intravenous drug self-administration in the cat is described. Ten cats were given 24-h access to methamphetamine reinforcement (0.04 mg/kg/inj). The subjects maintained a significantly higher response rate for drug reinforcement than for saline.
R L, Balster, M M, Kilbey, E H, Ellinwood   +2 more
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Cocaine self-administration in pigeons

Pharmacology Biochemistry and Behavior, 1991
Pigeons with chronic indwelling intravenous catheters responded under a multiple schedule of food and cocaine presentation. In one component, responding was maintained by food presentation under a fixed-ratio (FR 50) schedule, whereas in the other component, responding was maintained under the same schedule by IV infusions of cocaine (0.03 or 0.1 mg/kg/
P J, Winsauer, D M, Thompson
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Motivation for self-administration of LSD

The Psychiatric Quarterly, 1967
The reason for self-administration of LSD and the resulting subjective changes in 34 patients hospitalized following ingestion of LSD were studied. Only two patients were primarily interested in its reputed beneficial effects. Although 13 patients reported such effects, the authors were unable to document any objective improvement.
W A, Frosch, E, Robbins, L, Robbins, M, Stern   +3 more
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Self-administration of injectable contraceptives

Contraception, 2008
Although depot-medroxyprogesterone represents a highly effective contraceptive, its use is associated with poor continuation rates. Although the major reason for discontinuation is menstrual irregularity, the time, expense and inconvenience of clinic visits also pose a barrier to use.
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Self-Administration of Sedatives by Humans

1977
Sedative drugs have many of the same effects as alcohol. Taken in high doses, both produce confusion, difficulty in thinking, emotional lability, and motor incoordination (Isbell et al., 1950). Both also have a high potential for abuse, with tolerance and physiological dependence resulting from chronic, high-dose use (Wikler, 1968).
R, Pickens, M R, Cunningham, L L, Heston, E, Eckert, L K, Gustafson   +4 more
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Self-Administration of Diuretics

Annals of Internal Medicine, 1975
Excerpt To the editor: In 1972 our group reported three cases of hypokalemia of cryptogenic origin, which proved to be due to surreptitious self-administration of thiazide or "loop" diuretics, know...
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SELF-ADMINISTRATION OF BISHYDROXYCOUMARIN

American Journal of Psychiatry, 1964
J E, OLTMAN, S, FRIEDMAN
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Self-administration of brain-stimulation : an exploration of a model of drug self-administration

1990
This item was digitized as part of a project to share McGill's intellectual legacy with the public. If you are the copyright holder or a relative of the copyright holder who is deceased, you may request withdrawal by emailing escholarship.library@mcgill.ca.
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Drug self-administration

1993
Publisher Summary This chapter provides an overview of the concept of drug self-administration. The central feature of drug-reinforced behavior is the control of behavior by response-contingent presentation of the drug. In other words, the critical feature of drug-reinforced behavior is that the drug functions as a reinforcer.
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