Results 71 to 80 of about 5,906,664 (269)

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

The movement kinematics and learning strategies associated with adopting different foci of attention during both acquisition and anxious performance [PDF]

, 2012
Research suggests that implicit strategies adopted during learning help prevent breakdown of automatic processes and subsequent performance decrements associated with the presence of pressure.
Khan, M.A., Gavin Peter Lawrence, Khan, Michael A., Gottwald, V.M., Kramer, Robin S. S., Michael A. Khan, Kramer, R.S.S., Gavin P. Lawrence, Victoria M. Gottwald, Lawrence, Gavin P., Michael Angus Khan, Gottwald, Victoria M., Robin S. S. Kramer, Lawrence, G.P., Victoria Mary Gottwald, Robin S Kramer   +15 more
core   +1 more source

Relative molecule self-attention transformer

Journal of Cheminformatics
AbstractThe prediction of molecular properties is a crucial aspect in drug discovery that can save a lot of money and time during the drug design process. The use of machine learning methods to predict molecular properties has become increasingly popular in recent years.
Maziarka, Łukasz, Majchrowski, Dawid, Danel, Tomasz, Gaiński, Piotr, Tabor, Jacek, Podolak, Igor, Morkisz, Paweł, Jastrzębski, Stanisław   +7 more
openaire   +5 more sources

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

The relation of self-concept to desirable educational outcomes

, 2006
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda, Munns, Geoff, Ha, My Trinh, Martin, Andrew J.   +3 more
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

A comprehensive multilevel model meta-analysis of self-concept interventions

, 2006
The efficacy of self-concept interventions has previously been examined through traditional meta-analytic methods, and a host of moderators of intervention outcomes have been identified (O’Mara, Marsh, & Craven, 2004; Haney & Durlak, 1998; Hattie, 1992).
Craven, Rhonda, Marsh, Herbert W., O'Mara, Alison J.   +2 more
core  

The Philosopher and the Beetle: Attention, Self-Representation, and the Fate of Predictive Processing

I draw on work by John Perry to argue that the standard predictive processing theory of attention (SPPA) has the surprising consequence that any agent endowed with a predictive architecture and the capacity for attention can explicitly represent itself ...
Wotton, Frank
core   +1 more source

Shifts of attention in the early blind: an ERP study of attentional control processes in the absence of visual spatial information [PDF]

, 2006
To investigate the role of visual spatial information in the control of spatial attention, event-related brain potentials (ERPs) were recorded during a tactile attention task for a group of totally blind participants who were either congenitally blind or
van Velzen, J., Eimer, M., Eardley, Alison F., Eimer, Martin, Van Velzen, Jose L., Eardley, A., Eardley, A.F., Forster, B.   +7 more
core   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source