Results 51 to 60 of about 5,906,664 (269)
Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni +11 more
wiley +1 more source
The role of attention in monitoring second language speech production. [PDF]
The study investigates the role of attention in monitoring second language speechproduction by means of analyzing the distribution and frequency of self-repairs and the correction rate of errors in the speech of 30 Hungarian learners of English at 3 ...
Judit Kormos, Kormos, Judit
core
When "It" becomes "Mine": attentional biases triggered by object ownership. [PDF]
Previous research has demonstrated that higher-order cog- nitive processes associated with the allocation of selective atten- tion are engaged when highly familiar self-relevant items are encountered, such as oneðs name, face, personal possessions and ...
Brebner, Joanne +11 more
core +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
A Unified Generative Adversarial Network Training via Self-Labeling and Self-Attention
We propose a novel GAN training scheme that can handle any level of labeling in a unified manner. Our scheme introduces a form of artificial labeling that can incorporate manually defined labels, when available, and induce an alignment between them.
Favaro, Paolo, Watanabe, Tomoki
core
Differential Gated Self-Attention
Transformers excel across a large variety of tasks but remain susceptible to corrupted inputs, since standard self-attention treats all query-key interactions uniformly. Inspired by lateral inhibition in biological neural circuits and building on the recent use by the Differential Transformer's use of two parallel softmax subtraction for noise ...
Elpiniki Maria Lygizou +2 more
openaire +2 more sources
Electricity Theft Detection with self-attention
In this work we propose a novel self-attention mechanism model to address electricity theft detection on an imbalanced realistic dataset that presents a daily electricity consumption provided by State Grid Corporation of China. Our key contribution is the introduction of a multi-head self-attention mechanism concatenated with dilated convolutions and ...
Paulo Finardi +6 more
openaire +2 more sources
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner +7 more
wiley +1 more source

