Results 91 to 100 of about 8,906,254 (306)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Design and Numerical Investigation of Novel Self-Centering Precast Concrete Beam-Column Joints with Replaceable Damage-Controllable Hinges

open access: yesInternational Journal of Concrete Structures and Materials
To minimize the seismic damage to the beam-column joint and facilitate post-earthquake repair, an innovative precast concrete (PC) beam-column joint (SCPJ) with self-centering and damage-controllable capacities was proposed.
Chunxu Hou   +4 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Research on Design Methodology and Finite Element Analysis of Inner Cores for Multi-Level Energy Dissipation and Self-Centering BRBs—Part II: Self-Centering Circular Frustum Device

open access: yesBuildings
This paper introduces an innovative inner core for buckling-restrained braces, referred to as the Aluminum-Engineered Cementitious Composite-Circular Frustum Composite (ALECCYT) inner core, which incorporates multi-stage energy dissipation mechanisms and
Lixiang Cai   +6 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Resilient self-centering viscous-based bracing with SMA and friction springs: Multi-objective control of displacement and acceleration – an analytical study

open access: yesResilient Cities and Structures
Self-Centering Piston-Based Braced Frames (SC-PBBFs) are designed to curtail structural damage under severe ground motions. The self-centering mechanism in this bracing mitigates structural damage during an earthquake, thereby reducing post-earthquake ...
Navid Rahgozar, M.Shahria Alam
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

CONTACT MECHANISM AND SELF-CENTERING

open access: yesVeredas do Direito
The phenomena of self-centering accompany any contact of two bodies. For bodies with a small mass and low dynamic indicators, this phenomenon can be neglected. At high values of the dynamic indicators of the mechanical system and especially under periodic loading, the phenomenon of self-centering cannot be neglected, since its consequences accumulate ...
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

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