Results 31 to 40 of about 14,235 (263)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Improving the accuracy of machining of non-rigid shaft
MATEC Web of Conferences, 2018 So far, due to much more strict events of operating parameters requirements, the reduction of pieces steel intensity allows to produce multiplying quantity of the highly precise Non-Rigid Pieces (NRP); most of them are supposed to be the shafts in amount.
Drachev Oleg +2 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
BuildingsTo meet the recent requirements of low-damage design, there is a growing need to retrofit building structures with a self-centering dissipation system.
Asad Naeem, Kusunoki Koichi, Joohno Lee
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Investigation on Seismic Performance of Bridge with Self-centering Friction Dampers
工程科学与技术, 2018 Seismic isolation has been already applied in bridges widely. It will inevitably cause large post-earthquake residual displacement between bridge superstructure and substructure.
Yunshuai LIU, Jianping HAN, Xiaoqin WANG
doaj
Self-centering Capability of Seismically Isolated Structures After Earthquakes
工程科学与技术, 2023 The deformation of the isolated structure is mostly concentrated in the isolation layer due to its low stiffness. Isolation bearings commonly meet the requirement of a large deformation well under strong earthquakes.
Bin WANG +4 more
doaj
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Experimental Study on the Seismic Behavior of CFST Self-Centering Rocking Bridge Piers
BuildingsCompared to conventional reinforced concrete (RC) piers, self-centering rocking piers exhibit better seismic resilience and sustain minor damage. However, their construction typically relies on prefabrication.
Wei Lu +4 more
doaj +1 more source