Results 51 to 60 of about 6,190,267 (241)

Autophagy in toxicology: self‐consumption in times of stress and plenty [PDF]

Journal of Applied Toxicology, 2012
ABSTRACTAutophagy is a critical cellular process orchestrating the lysosomal degradation of cellular components in order to maintain cellular homeostasis and respond to cellular stress. A growing research effort over the last decade has proven autophagy to be essential for constitutive protein and organelle turnover, for embryonic/neonatal survival and
Alicia M, Bolt, Walter T, Klimecki
openaire   +2 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

A Comparison of Direct and Indirect Flexibilities on the Self-Consumption of an Office Building: The Case of Predis-MHI, a Smart Office Building

Frontiers in Energy Research, 2022
The purpose of this paper is to provide a method for assessing the impact of direct and indirect flexibilities on the self-consumption of office buildings. The goal is to assess how both the human actors and technical interventions can affect or mitigate
Nana Kofi Twum-Duah, Nana Kofi Twum-Duah, Manar Amayri, Stéphane Ploix, Frédéric Wurtz   +4 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Extrativismo e Produção de Alimentos como Estratégia de Reprodução de Agricultores Familiares do Assentamento Seringal, Amazônia Meridional

Revista de Economia e Sociologia Rural
Resumo: A soberania alimentar do agricultor familiar está relacionada à transformação do agroecossistema, articulando a geração de trabalho e renda e sua capacidade de autoprodução de alimentos. Assim, este trabalho tem por objetivo investigar a produção
Keller Regina Soares, Esvanio Edipo da Silva Ferreira, Santino Seabra Junior, Sandra Mara Alves da Silva Neves   +3 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Effortless Inhibition: Habit Mediates the Relation Between Self-Control and Unhealthy Snack Consumption [PDF]

, 2014
In contrast to prevailing beliefs, recent research suggests that trait self-control promotes health behavior not because those high in self-control are more successful at resisting single temptations, but rather because they develop adaptive habits.
Marieke eAdriaanse, Kroese, Floor M., Denise eDe Ridder, Marieke A. Adriaanse, Floor M. Kroese, Stress and self-regulation, Floor eKroese, Denise T. D. De Ridder, Gillebaart, Marleen, Adriaanse, Marieke A., Marleen eGillebaart, Marleen Gillebaart, Leerstoel Ridder, De Ridder, Denise T D   +13 more
core   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

The New Spanish Self-consumption Regulation

Energy Procedia, 2016
Abstract The new Spanish Power Sector Law (Ley del Sector Electrico, LSE) 24/2013 regulates self-consumption facilities for the first time, and in particular domestic PV panels. The paper analyzes the approved regulation. It is concluded that energy prices and access tariffs should faithfully reflect actual supply costs, in order not to distort ...
Aragonés, Vanessa, Barquín, Julián, Alba, Juan   +2 more
openaire   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source