Results 71 to 80 of about 4,804,653 (297)

The Effectiveness of Emotion Focused Therapy on Alexithymia and Internalized Self-Criticism in Neurotic Perfectionist Girls [PDF]

Taḥqīqāt-i ̒Ulūm-i Raftārī, 2023
Aim and Background: The aim of the current study was to investigate the effectiveness of Emotion Focused Therapy on Alexithymia and Internalized Self-Criticism in Neurotic Perfectionist girls.
Zahra Khadem Dezfuli, Seyedeh Zahra Alavi, Masoud Shahbazi   +2 more
doaj  

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Actors and Vehicles of Architectural Criticism (4)

, 2016
From Satire to Criticism: Comics in Architecture Publications in the 1960s and 1970s Carlos Machado e Moura Faculdade de Arquitectura da Universidade do Porto Cartoons, in the tradition of the graphic satire, have been an acute form of criticism of ...
Mapping Architectural Criticism
core   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

The Effectiveness of Acceptance and Commitment Therapy on Self-Compassion and Self-Criticism in Individuals with Opioid Use Disorder [PDF]

Research on Addiction, 2020
Objective: Substance use disorder is one of the chronic and debilitating disorders. The aim of this study was to investigate the effectiveness of acceptance and commitment therapy on self-compassion and self-criticism in individuals with opioid use ...
Sanam Khamoshi Ghalenoei, Ahmad Mansouri
doaj  

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Growing Up with a Narcissistic Mother: Mediating Role of Self-Criticism in the Relationship of Maternal Narcissistic Traits with Depression and Anxiety

Psikiyatride Güncel Yaklaşımlar
Objective: This study aims to examine the mediating role of self-criticism in the relationship between narcissistic traits perceived from the mother in childhood and symptoms of depression and anxiety disorders in adulthood.
Emre Han Alpay, Arzu Aydın
doaj   +1 more source

Randomised Controlled Trial of an Online Version of Compassion Mind Training in a Nonclinical Sample

Europe's Journal of Psychology, 2020
Compassion Mind Training (CMT) is a therapeutic approach to guide highly self-critical individuals to generate compassion. The goal was to probe the efficacy of a short-term, online version of the CMT on self-compassion and self-criticism in a non ...
Júlia Halamová, Martin Kanovský, Alexandra Pačutová, Nuriye Kupeli   +3 more
doaj   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Architectural Criticism between Public Debate and Autonomous Discipline (4)

, 2016
Fixing boundaries. Architecture and criticism at the onset of the 20th century Rute Figueiredo gta/D-ARCH/ETH Zurich, Director of the Site of Discourse Research Project (Lisbon University) During the last few years, there has been an increasing interest ...
Mapping Architectural Criticism
core   +1 more source