Advanced Science, EarlyView.A mitochondria‐targeted copper depletion nanoplatform (CYN‐CDA@Alb) was developed to selectively disrupt tumor mitochondria copper, which then reprogrammed the tumor immune microenvironment by depressing PD‐L1 and CD47 expression simultaneously. By doing this, CYN‐CDA@Alb reversed radiotherapy‐induced immune tolerance, showing the potential usage of ...
Zaigang Zhou +10 more
wiley +1 more source
Understanding and improving responses to suicidality for Department of Veterans' Affairs clients in Queensland: a data linkage study - project protocol. [PDF]
BMJ OpenMeurk CS +8 more
europepmc +1 more source
The global systemic crisis and the requirements of a whiteheadian socialism [PDF]
, 2014 Weber, Michel +2 more
core
Advanced Science, EarlyView.It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou +8 more
wiley +1 more source
Prediction of academic outcomes by serum cortisol, perceived academic stress, perceived memory performance, and physical activity among preclinical undergraduate medical students: a short-term observational study. [PDF]
BMC PsycholGanesh P +9 more
europepmc +1 more source
Biolipid Film‐Fused Electrochemiluminescence for Multipurpose In Situ Bioassays
Advanced Science, EarlyView.An ECL‐emissive, membrane‐interactive scaffold was fabricated, and facilely fused with natural and non‐native phospholipids into multifactorial mimicries of cytomembranes and vesicles for in vitro representative membrane‐process probing. Such a biointerface‐based, state‐sensitive ECL paradigm not only pinpointed proximal phenomena, including channeling
Jialiang Chen +9 more
wiley +1 more source
Integrated Blood Biomarker and Neurobehavioural Signatures of Latent Neuroinjury in Experienced Military Breachers Exposed to Repetitive Low-Intensity Blast. [PDF]
Int J Mol SciDi Battista AP +7 more
europepmc +1 more source
Advanced Science, EarlyView.This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin +14 more
wiley +1 more source
Human augmentation to deliver an enhanced and resilient people capability for Defence. [PDF]
BMJ Mil HealthCasey A +5 more
europepmc +1 more source