Results 51 to 60 of about 88,043 (299)

Beyond Technique: The Limits of Books (and Online Videos) in Developing Self-Defence Coaches’ Professional Judgement and Decision Making in the Context of Skill Development for Violent Encounters

Acta Periodica Duellatorum, 2020
The depiction and description of body techniques of combat have always been a part of martial arts culture. For example, self-defence techniques of the Israeli system of Krav Maga have routinely been depicted and described in books.
Mario Staller, Swen Körner, Andrew Abraham   +2 more
doaj   +1 more source

Defenceless castles: the use of grossly disproportionate force by householders in light of R (Collins) v Secretary of State for Justice [2016] EWHC 33 (Admin) [PDF]

, 2016
On 16 January 2016, the Divisional Court gave judgment in the case of Collins. In the judgment, Sir Brian Leveson P provided an authoritative statement as to the meaning of ‘grossly disproportionate’ within the law of self-defence for householders. First
Thomas, MP
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Self-Defence as a Circumstance Precluding the Wrongfulness of the Use of Force

Utrecht Law Review, 2015
Roberto Ago, the International Law Commission’s second Special Rapporteur on the topic of state responsibility for internationally wrongful acts, defined self-defence as a faculté of a state to use force in response to an act of another state through ...
Cliff Farhang
doaj   +1 more source

Hätävarjelun ja hätävarjelun liioittelun rajat [PDF]

, 2017
Tässä opinnäytetyössä käsiteltiin hätävarjelua ja hätävarjelun liioittelua sekä niiden välisiä rajoja. Tavoitteena oli selvittää, mitä edellytyksiä kuuluu hätävarjeluun ja hätävarjelun liioitteluun sekä missä menee näiden raja ja mitkä asiat ovat ...
Tolonen, Sarita
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Not quite the 'Great Britain of the Far East': Japan's security, the US-Japan alliance and the 'war on terror' in East Asia [PDF]

, 2007
Japan, in responding to US expectations for support in the 'war on terror', has displayed a degree of strategic convergence on global security objectives, thus prompting policy-makers and observers to dub it the 'Great Britain of the Far East'.
Christopher W Hughes, Dosch Jörn, Haacke Jürgen, Hitoshi Tanaka, Hughes Christopher W, Hughes Christopher W, Hughes Christopher W, Hughes Christopher W, Hughes Christopher W, Kamiya Matake, Katō Yōichi, Leheny David, Soeya Yoshihide, Tanter Richard   +13 more
core   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

UŻYWANIE DRONÓW W CELU ZWALCZANIA TERRORYZMU ŚWIETLE ‘IUS AD BELLUM’

Zeszyty Prawnicze, 2016
The Use of Drones in Combating International Terrorism from the Perspective of ‘ius ad bellum’ Summary The increasing practice of using armed unmanned aerial vehicles (military UAVs, commonly known as drones) by some countries to eliminate suspected ...
Łukasz Kułaga
doaj   +1 more source