Results 91 to 100 of about 1,350,060 (297)

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

LEARNING MOTIVATION: A SELF-DETERMINATION THEORY PERSPECTIVE

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei, 2014
MOTIVAŢIA ÎNVĂŢĂRII DIN PERSPECTIVA TEORIEI AUTODETERMINĂRII În ultimii ani reapare interesul faţă de problematica dezvoltării motivaţiei studenţilor.
USM ADMIN
doaj  

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Conjuring up the correspondence of high-school students’ self-determination and classroom climate with reading achievement

open access: yesEnglish Language Teaching Educational Journal, 2020
A prevalent goal of education in schools is reading comprehension enhancement. Therefore, a critical issue in   educational psychology is investigating the factors contributing to increase the reading achievement including both classroom climate and ...
Shahrbanoo Joulide   +2 more
doaj   +1 more source

Non-Perturbative Study of the Light Pseudoscalar Masses in Chiral Dynamics [PDF]

open access: yes, 2006
We perform a non-perturbative chiral study of the masses of the lightest pseudoscalar mesons. In the calculation of the self-energies we employ the S-wave meson-meson amplitudes taken from Unitary Chiral Perturbation Theory (UCHPT) that include the ...
Aitala)   +69 more
core   +4 more sources

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Predicting Students’ Physical Activity and Health-Related Well-Being: A Prospective Cross-Domain Investigation of Motivation Across School Physical Education and Exercise Settings \ud [PDF]

open access: yes, 2012
A three-wave prospective design was used to assess a model of motivation guided by self-determination theory (Ryan & Deci, 2008) spanning the contexts of school physical education (PE) and exercise.
Gillison, Fiona B   +3 more
core   +1 more source

The McCance Brain Care Score and Mortality: Evidence From a Large‐Scale Population‐Based Cohort

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives This study aimed to examine the relationship between the McCance Brain Care Score (BCS) and mortality in the general population. Methods We conducted a prospective, population‐based cohort study using data from the UK Biobank. Participants with complete data enabling calculation of BCS and full mortality information were included ...
Zhiqiang Xu, Xiaoxiao Wang, Nan Li
wiley   +1 more source

Deportividad en balonmano : un análisis desde la Teoría de la Autodeterminación [PDF]

open access: yes, 2011
This study analyses a model proposed to explain players' perception of sportsmanlike behaviours using a causal sequence proposed by the self-determination theory (Vallerand, 1997, 2001).
Guzmán Luján, José Francisco   +1 more
core   +2 more sources

Understanding the Coping Process from a Self-Determination Theory Perspective [PDF]

open access: yes, 2009
Purpose: To explore conceptual links between the Cognitive-Motivational-Relational Theory of coping (Lazarus, 1991) and Self-Determination Theory of motivation (Deci & Ryan, 1985) Method: We present a very brief overview of the two theories.
Duda, Joan L   +2 more
core   +1 more source

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