Results 51 to 60 of about 5,817,872 (291)

Epigenetic reprogramming of lineage switching in cancer

open access: yesFEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı   +4 more
wiley   +1 more source

Combinational Circuits Testing Based on Hsiao Codes with Self-Dual Check Functions

open access: yesComputation
This paper investigates the features of using modified Hamming codes, which are also known as Hsiao codes. Self-checking digital devices are proposed to be implemented with calculations testing using two diagnostic signs.
Dmitry V. Efanov   +6 more
doaj   +1 more source

On the Hamming Distances of Constacyclic Codes of Length 5pS

open access: yesIEEE Access, 2020
Let $p$ be a prime, $s$ , $m$ be positive integers, and $\lambda $ be a nonzero element of the finite field $\mathbb {F}_{p^{m}}$ . In this paper, the algebraic structures of constacyclic codes of length $5~p^{s}~(p\neq 5)$ are obtained, which ...
Hai Q. Dinh   +2 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

PERSYMMETRIC MATRIX AND ITS APPLICATION IN CODING THEORY

open access: yesBarekeng
A persymmetric matrix is a square matrix that is symmetric concerning its antidiagonal. This article discusses some characteristics of a persymmetric matrix and its application in coding theory. A persymmetric matrix is used to form a generator matrix of
Ardi Nur Hidayat   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Z₂Z₄-additive formally self-dual codes

open access: yes, 2014
We study odd and even Z₂Z₄ formally self-dual codes. The images of these codes are binary codes whose weight enumerators are that of a formally self-dual code but may not be linear. Three constructions are given for formally self-dual codes and existence
Fernández Córdoba, Cristina   +1 more
core   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Binary formally self-dual odd codes

open access: yes, 2017
Most of the research on formally self-dual (f.s.d.) codes has been developed for binary f.s.d. even codes, but only limited research has been done for binary f.s.d. odd codes. In this article we complete the classification of binary f.s.d.
이윤진, 이혜숙
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

open access: yesMolecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

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