Results 71 to 80 of about 290,159 (337)

The Build-Up Construction for Codes over a Commutative Non-Unitary Ring of Order 9

Mathematics
The build-up method is a powerful class of propagation rules that generate self-dual codes over finite fields and unitary rings. Recently, it was extended to non-unitary rings of order 4, to generate quasi self-dual codes.
Adel Alahmadi, Tamador Alihia, Rowena Alma Betty, Lucky Galvez, Patrick Solé   +4 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Combinational Circuits Testing Based on Hsiao Codes with Self-Dual Check Functions

Computation
This paper investigates the features of using modified Hamming codes, which are also known as Hsiao codes. Self-checking digital devices are proposed to be implemented with calculations testing using two diagnostic signs.
Dmitry V. Efanov, Tatiana S. Pogodina, Nazirjan M. Aripov, Sunnatillo T. Boltayev, Asadulla R. Azizov, Elnara K. Ametova, Feruza F. Shakirova   +6 more
doaj   +1 more source

On the Hamming Distances of Constacyclic Codes of Length 5p^S

IEEE Access, 2020
Let $p$ be a prime, $s$ , $m$ be positive integers, and $\lambda $ be a nonzero element of the finite field $\mathbb {F}_{p^{m}}$ . In this paper, the algebraic structures of constacyclic codes of length $5~p^{s}~(p\neq 5)$ are obtained, which ...
Hai Q. Dinh, Xiaoqiang Wang, Jirakom Sirisrisakulchai   +2 more
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

PERSYMMETRIC MATRIX AND ITS APPLICATION IN CODING THEORY

Barekeng
A persymmetric matrix is a square matrix that is symmetric concerning its antidiagonal. This article discusses some characteristics of a persymmetric matrix and its application in coding theory. A persymmetric matrix is used to form a generator matrix of
Ardi Nur Hidayat, Vira Hari Krisnawati, Abdul Rouf Alghofari   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Optimal ternary formally self-dual codes [PDF]

, 1999
In this paper, we study ternary optimal formally self-dual codes. Bounds for the highest minimum weight are given for length up to 30 and examples of optimal formally self-dual codes are constructed.
Steven T. Dougherty, Masaaki Harada, Aaron Gulliver, T., Harada, Masaaki, Dougherty, Steven T., T. Aaron Gulliver   +5 more
core   +1 more source

Composite constructions of self-dual codes from group rings and new extremal self-dual binary codes of length 68

Advances in Mathematics of Communications, 2020
We describe eight composite constructions from group rings where the orders of the groups are 4 and 8, which are then applied to find self-dual codes of length 16 over \begin{document}$ \mathbb{F}_4 $\end{document} .
S. Dougherty, J. Gildea, A. Korban, A. Kaya   +3 more
semanticscholar   +1 more source