Results 41 to 50 of about 5,737,714 (236)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

THE CONCEPT OF SELF-EFFICACY AND SELF-EFFICACY-PERFORMANCE RELATIONSHIP

Ankara Üniversitesi SBF Dergisi, 2000
Self-Efficacy (SE) is the belief or perception of a pcrson that he or she is capable to perform a specific task. It is a dynamic element that influenccs other concepts such as goals, performance and is influenced by them. SE is an essential element in Social Cognitive Learning Theory.
openaire   +3 more sources

Social–emotional competencies among teachers: An examination of interrelationships

Cogent Education, 2016
Teachers’ social–emotional competence is crucial for promoting a positive learning environment to the students. However, the research on teachers’ social–emotional abilities is very limited.
Meirav Hen, Marina Goroshit
doaj   +1 more source

The Effect of Task-Based Language Instruction on Shambu Secondary Students’ Speaking Self-Efficacy Beliefs and Benefits

Journal of Languages and Language Teaching, 2023
TBLT represents an approach to language learning that prioritizes meaning but does not neglect form. It emphasizes the importance of engaging students' natural abilities to acquire language incidentally as they engage with language as a meaning-making ...
Moti Alemayehu Dheressa, Tamiru Olana, Ebisa Bekele   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Perceptions of Self-Efficacy for Inclusive Classroom Practices: a Survey of Italian EFL Teachers [PDF]

, 2023
openThe study aims at investigating the perceptions of self-efficacy for inclusive practices of Italian EFL teachers, given the fact that teachers' perceptions of self-efficacy appear to be related to a higher probability that they implement inclusive ...
ALFIERI, BEATRICE
core  

Relationship Between Self Efficacy And Self Regulation In Diabetes Mellitus Patients

Professional Health Journal
Diabetes Mellitus is an incurable disease that affects aspects of life and increases the risk of complications that can cause death. Complications can be minimized if the patient has compliance, knowledge, and ability to perform self-care .
Devi Setya Putri, Alvina Setiani, Luluk Cahyanti   +2 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source