Results 51 to 60 of about 7,455,437 (248)

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

The mediating role of self-efficacy in the development of entrepreneurial intentions.

Journal of Applied Psychology, 2005
The purpose of this study was to investigate the mediating role of self-efficacy in the development of students' intentions to become entrepreneurs. The authors used structural equation modeling with a sample of 265 master of business administration ...
Hao Zhao, S. Seibert, G. Hills
semanticscholar   +1 more source

The Role of Self-Efficacy in Job Satisfaction, Organizational Commitment, Motivation and Job Involvement

Eurasian Journal of Educational Research, 2020
Purpose: Self-efficacy belief procures teachers to root for each other’s development in some issues such as ameliorating new methods to conduct much more effective teaching.
S. Demir
semanticscholar   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

Molecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi, Mandy Berndt‐Paetz, Eileen Lerner, Gregoire Najjar, Anca Azoitei, Krishna Pal Singh, Shailendra Kumar Gupta, Olaf Wolkenhauer, Cagatay Günes, Otmar Huber, Marc‐Oliver Grimm, Daniel Steinbach   +11 more
wiley   +1 more source

Research Self-efficacy among Postgraduate Students at Birjand University of Medical Sciences [PDF]

مجله ایرانی آموزش در علوم پزشکی, 2018
Introduction: Research self-efficacy is the main factor influencing successful administration and pursuing of research by postgraduate students. This study aimed to determine research self-efficacy among postgraduate students at Birjand University of ...
Mohammad Reza Miri, Hamid Salehiniya, Maryam Bahlgerdi, Asma Tiyuri, Amir Tiyuri   +4 more
doaj  

An Investigation into Information Literacy Self-efficacy Dimensions of Post Graduate Students: A Case Study [PDF]

تحقیقات کتابداری و اطلاع‌رسانی دانشگاهی, 2017
Purpose: the present study aims to investigate Information Literacy Self-efficacy in post graduate student of Shahed University, Iran. In doing so, a review of literature concerning the main concepts of self-efficacy, Information Literacy Self-efficacy ...
حمید کشاورز, امیر وفائیان, محمدرضا شکاری   +2 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Development and Validation of a Self-Efficacy Scale with Writing and Social Factors

Asian Journal of Assessment in Teaching and Learning, 2016
As a useful base for scale development, self-efficacy construct can be used in measuring competency and self-perception of individuals in their social behavior and academic achievements. The aim of this study was to develop a self-efficacy scale with two
Sadegh Soheili Anaraki, Seyed Mohammad Reza Amirian, Moslem Zolfagharkhani   +2 more
doaj  

Impact of Teacher Self-Efficacy on Secondary School Students’ Academic Achievement [PDF]

Journal of Education and Educational Development, 2017
The study of self-efficacy and its impact on human performance has intrigued many scholars during the last two decades, for example, Clayson and Sheffet, 2006; Nauta, 2004; Muijsand Rejnolds 2001; Bandura, 1997 and Soodak and Podell, 1993. This study was
Khurram Shahzad, Sajida Naureen
doaj   +1 more source