Results 71 to 80 of about 5,951,570 (340)
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
Entrepreneurial motivation and self-employment: evidence from expectancy theory
The International Entrepreneurship and Management Journal, 2017 One effect of the economic crisis on the business world has been the drastic reduction in staff and this in turn highlights the need for self-employment and the creation of new companies to establish a solid industrial fabric to support the creation of ...
Virginia Barba-Sánchez +1 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Self-employment and well-being across institutional contexts
Journal of Business Venturing, 2019 This paper investigates whether the relationship between a person's occupational status and well-being differs across countries with varying institutional contexts.
M. Fritsch +2 more
semanticscholar +1 more source
Self-employment in Britain: when, who and why? [PDF]
, 2004 This work explores self-employment in Britain across recent years with a particular focus on when individuals became self-employed, who is more or less likely to enter self-employment and why individuals choose to enter self-employment.
Taylor, Mark P.
core +1 more source
Digital twins to accelerate target identification and drug development for immune‐mediated disorders
FEBS Open Bio, EarlyView.Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley +1 more source
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Cogent Economics & FinanceDespite numerous policies implemented in this respect, Ghana still needs to catch up in achieving the Sustainable Development Goal of ending poverty in all forms by 2030.
Kwame Adjei-Mantey, Mark Edem Kunawotor
doaj +1 more source
Consequences of employment self–etching primer adhesive in orthodontic practice [PDF]
Al-Rafidain Dental Journal, 2004 The purposes of this study were to evaluate the shear bonding strength of stainless steel brackets bonded with self–etching primer adhesive system (Trans-bondTM 3M Uniteck, Monrovia, California, USA), compared with same system which employ 35% phosphoric
Ali R Al–Khatib
doaj +1 more source
FEBS Open Bio, EarlyView.Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source