Results 31 to 40 of about 4,486,589 (342)

The Relationship Between Self-Control and Self-Efficacy Among Patients With Substance Use Disorders: Resilience and Self-Esteem as Mediators

open access: yesFrontiers in Psychiatry, 2019
Background: While substance use disorder is one of the overarching health and social issues that might seriously disrupt individuals’ self-control and self-efficacy, most previous studies have been conducted among university students or other groups, and
Chunyu Yang   +4 more
semanticscholar   +1 more source

Youth Empowerment Programs for Improving Self‐Efficacy and Self‐Esteem of Adolescents

open access: yesCampbell Systematic Reviews, 2011
Do youth empowerment programs improve adolescents' self‐esteem and self‐efficacy? A Campbell systematic review of international research suggests that there is not enough reliable evidence to substantiate the popular expectation that these programs are ...
Matthew Morton, Paul Montgomery
doaj   +1 more source

Enhancing Self Esteem of Orphan Teenagers through Self Discovery Training

open access: yesPsympathic: Jurnal Ilmiah Psikologi
This study aims to (1) determine the effect of self-discovery training and (2) provide a description of the changes in self-esteem after the intervention. The procedures were carried out using the quantitative pre-experimental method with a group pretest-
Ema Zati Baroroh   +3 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Detecting homologous recombination deficiency for breast cancer through integrative analysis of genomic data

open access: yesMolecular Oncology, EarlyView.
This study develops a semi‐supervised classifier integrating multi‐genomic data (1404 training/5893 validation samples) to improve homologous recombination deficiency (HRD) detection in breast cancer. Our method demonstrates prognostic value and predicts chemotherapy/PARP inhibitor sensitivity in HRD+ tumours.
Rong Zhu   +12 more
wiley   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

IMPACT OF SELF ESTEEM & SUPPORT ON STUDENT PERFORMANCE [PDF]

open access: yesManagement & Marketing, 2012
Education is life blood for development of country. This paper explores the impact of various factors on student performance. Data was collected from ten (10) Govt. & Private schools in Rawalpindi.
Akmal SHAHZAD   +3 more
doaj  

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Self and Body Esteem Perception in Multiple Sclerosis

open access: yesBehavioural Neurology, 1999
Self esteem and body esteem were examined in a group of 35 relapsing-remitting multiple sclerosis (MS) patients using the Body Esteem Scale (BES) and the Eysenck Self Esteem Scale (ESES) and compared to age and sex matched normal controls.
Yoram Barak   +3 more
doaj   +1 more source

Decrypting cancer's spatial code: from single cells to tissue niches

open access: yesMolecular Oncology, EarlyView.
Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik   +4 more
wiley   +1 more source

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