Results 61 to 70 of about 4,064,726 (298)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Contingencies of Self-Worth and Social-Networking-Site Behavior [PDF]

, 2011
Social-networking sites like Facebook enable people to share a range of personal information with expansive groups of "friends." With the growing popularity of media sharing online, many questions remain regarding antecedent conditions for this behavior.
Lackaff, Derek, Rosen, Devan, Stefanone, Michael A.   +2 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Sitting with others: mental health self-help groups in northern Ghana

International Journal of Mental Health Systems, 2012
Background Over the past four decades, there has been increasing interest in Self-Help Groups, by mental health services users and caregivers, alike. Research in high-income countries suggests that participation in SHGs is associated with decreased use ...
Cohen Alex, Raja Shoba, Underhill Chris, Yaro Badimak, Dokurugu Adam, De Silva Mary, Patel Vikram   +6 more
doaj   +1 more source

Self Help Groups and empowerment of women: Self-selection or actual benefits? [PDF]

Evidence on success of SHGs in empowering females is mixed. In particular, researchers argue that such schemes often attract women who are already active in the public domain (referred to as ‘self-selection’), so that those who are most in need of ...
Dutta, Mousumi, Husain, Zakir, Mukherjee, Diganta   +2 more
core   +1 more source

Being a ‘Self-Help Supporter’: Recognising the roles that community practitioners can adopt in supporting self-help groups [PDF]

, 2017
Recent policies on self-care and personalisation have a strong focus on the value of peers as a means through which understanding and knowledge can be conveyed.
Avis, Mark, Boyce, Melanie J., Chaudhary, Sarah, Munn-Giddings, Carol, Seebohm, Patience   +4 more
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Empowering Parents: The Impact of a Parenting Practice-Based Care Module on Preventing Internet Gaming Disorder in Elementary School Children

Iranian Journal of Nursing and Midwifery Research
Background: The prevalence of Internet Gaming Disorder (IGD) among elementary school children has raised concerns about its potential negative impact on academic performance, social interactions, and overall mental well-being.
Nur Hidaayah, Esti Yunitasari, Hanik Endang Nihayati   +2 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source