Results 111 to 120 of about 919,354 (307)

Seeking Anonymity in an Internet Panopticon

open access: yes, 2015
Obtaining and maintaining anonymity on the Internet is challenging. The state of the art in deployed tools, such as Tor, uses onion routing (OR) to relay encrypted connections on a detour passing through randomly chosen relays scattered around the ...
Feigenbaum, Joan, Ford, Bryan
core   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

open access: yesAging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu   +8 more
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

open access: yesAging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Intermarriage and the Intergenerational Transmission of Ethnic Identity and Human Capital for Mexican Americans [PDF]

open access: yes
Using microdata from the 2000 U.S. Census and from recent years of the Current Population Survey (CPS), we investigate whether selective intermarriage and endogenous ethnic identification interact to hide some of the intergenerational progress achieved ...
Brian Duncan, Stephen Trejo
core  

Идентификация и самоидентификация как первичные и вторичные факторы саморазвития личности педагога [PDF]

open access: yes, 2007
У статті розглядається роль та місце професійної та особистісної самоідентифікації в структурі ідентичності педагога. Окреслюються перспективи використання самоідентифікації як психологічного механізму подолання кризи професійної ідентичності ...
Zlivkov, V.   +2 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

open access: yesAging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang   +3 more
wiley   +1 more source

Lost in Self-Identification?

open access: yesPolitikon, 2015
The main purpose of the research is to analyze how NATO’s identity is constructed through the discourses from three NATO Summits – Lisbon, Chicago and Wales. The research is based on post-structuralistic theoretical background which emphasizes the role of identity in the context of security policies.
openaire   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

open access: yesAging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss   +12 more
wiley   +1 more source

Patterns of Asexuality in the United States [PDF]

open access: yes
In this paper we use data from the 2002 National Survey of Family Growth (NSFG) to ascertain and analyze patterns of asexuality in the United States. We endeavor to extend the earlier work of Bogaert (2004) on this topic, which focused on patterns of ...
Amanda Baumle, Dudley L. Poston
core  

The enterprise as a fractal formation: self-identification and development [PDF]

open access: yes, 2013
The sustainable development issue encompasses a wide range of important economic, social and ecological problems. Their complexity, multi-level and interconnection require appropriate conceptual and methodological approaches.
Shevtsova, A.Z.
core  

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