Results 81 to 90 of about 17,130,308 (347)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

An Integrative Model of Social Identification: Self-Stereotyping and Self-Anchoring as Two Cognitive Pathways [PDF]

open access: yes, 2016
Social identification denotes individuals’ psychological bond with their ingroup. It is an indispensable construct in research on intragroup and intergroup dynamics.
CADINU, MARIA ROSARIA   +10 more
core   +1 more source

CENTAUR-PARADOXES OF ECONOMIC CONSCIOUSNESS OF RUSSIAN ENTREPRENEURSHIP

open access: yesВестник Донского государственного технического университета, 2018
Basic coordinates of the economic consciousness of the Russian business are considered. It is revealed, that subjectlessness, expolarity, diffusion of the Russian economy have formed multidirectional attitudes in the economic consciousness of business ...
Mikhail N. Mikheyev
doaj  

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The “Diagnosis of Personal and Professional Feasibility” Methodology: Structure and Psychometric Justification

open access: yesBulletin of Kharkiv National University of Internal Affairs
The article presents the results of the development and psychometric testing of the author’s methodology “Diagnostics of personal and professional feasibility”, which is a tool for comprehensive assessment of personal and professional components of ...
Ya. S. Ponomarenko
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Ethnic Self-Identification of First-Generation Immigrants [PDF]

open access: yes
This paper uses the concept of ethnic self-identification of immigrants in a twodimensional framework. It acknowledges the fact that attachments to the home and the host country are not necessarily mutually exclusive.
Amelie Constant   +2 more
core  

Self-identification of the Belarusian-speaking Population of the Grodno Region and its Surroundings in Previous Centuries and of the Sokółka Region Today

open access: yesActa Albaruthenica
The aim of this article is to describe the historical and modern ethnonyms of the Belarusian-speaking population in the Grodno region and to investigate whether and how much they have changed.
Mateusz Jan Kwiatkowski
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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