Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Positive Self-Image and Incentives in Organizations [PDF]
This paper investigates the implications of individuals’ mistaken beliefs of their abilities on incentives in organizations using the principal-agent model of moral hazard.
Pinto, Luis Santos
core +3 more sources
Radical research as research at the roots: Practitioner self-image, public relations and ethics [PDF]
, 2008 Semantically, radical derives from ‘radix’, the Latin for root. This paper argues that little public relations research goes back to the roots of actual practice and addresses this neglect through a project focusing on practitioner accounts of their work.
Toledano, Margalit
core +1 more source
The experiences of medical students and junior doctors with dyslexia: a survey study [PDF]
, 2020 Little research exists concerning dyslexia in medical education. A qualitative study highlighted issues such as bullying and a lack of support. This project aimed to quantify those findings.
Anderson, John L, Shaw, Sebastian C K
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
A Life of the ‘Other’ and a Story of the ‘Self’: Shivarani Devi in "Premcand ghar me͂"
Cracow Indological Studies, 2018 A Life of the ‘Other’ and a Story of the ‘Self’: Shivarani Devi in "Premcand ghar me͂" This paper will deal with Shivarani Devi’s (1890–1976) Premcand ghar mẽ, a literary memoir-cum-biography of her husband Premchand, a pioneer of Hindi literature ...
Alaka Atreya Chudal
doaj +1 more source
Exploiting Generative Self-Supervised Learning For The Assessment of Biological Images With Lack of Annotations: A COVID-19 Case-Study [PDF]
, 2021 Alessio Mascolini +4 more
openalex +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Four aspects of self-image close to death at home
International Journal of Qualitative Studies on Health & Well-Being, 2011 Living close to death means an inevitable confrontation with one's own existential limitation. In this article, we argue that everyday life close to death embodies an identity work in progress.
Ida Carlander +4 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source