Results 51 to 60 of about 4,486,736 (297)

Disrupting Helicobacter pylori Iron Homeostasis With Bismuth Nanodrug‐Mediated Nutritional Trap for Targeted Gastric Infection Therapy

open access: yesAdvanced Science, EarlyView.
A “nutritional trap” strategy centered on disrupting bacterial iron homeostasis is proposed. The synthesized Bi‐TP@FU (TBF) can target Helicobacter pylori, interfere with the bacterial iron uptake and utilization processes to disrupt its iron homeostasis, induce bacterial death, and meanwhile preserve the balance of the intestinal flora.
Tianye Fang   +13 more
wiley   +1 more source

Self-injury in teenagers [PDF]

open access: yes, 2009
Includes bibliographical ...
Larsen, Kristina
core  

Multifunctional Manganese Oxide Nanocomposite Hydrogel With Synergistic Reactive Oxygen Species‐Scavenging, Oxygen‐Generating, Immunomodulatory, and Photothermal Antimicrobial Activities for Enhanced Diabetic Wound Healing

open access: yesAdvanced Science, EarlyView.
CFP/PC@MnO2 hydrogel integrates ROS scavenging, oxygen delivery, oxidative stress reduction, immunomodulation, and photothermal antibacterial properties. The incorporation of PC@MnO2 NPs endows the hydrogel with multiple functional advantages tailored to the pathological microenvironment of diabetic wounds, including efficient ROS clearance, mitigation
Zhi Xu   +9 more
wiley   +1 more source

Review of Gastrointestinal Capsule Robots: Materials, Actuation, Diagnostics, and Therapeutics

open access: yesAdvanced Science, EarlyView.
This review examines gastrointestinal capsule robots through a systems engineering lens, covering shell materials, actuation and localization strategies, diagnostic modalities, therapeutic interventions, and commercialization status. By mapping the complete technological chain from fabrication to clinical deployment, this work identifies critical gaps ...
Zengsheng Li   +8 more
wiley   +1 more source

An unusual case of self-inflicted stab injury to brain under alcohol intoxication without any behavioral or cognitive sequelae

open access: yesJournal of Mental Health and Human Behaviour, 2017
Intracranial injuries related to trauma, homicidal attacks, gunshot, or accidental injuries are commonly seen in emergency department. However, self-inflicted intracranial injuries are rarely described. In this report, we present a case of self-inflicted
Aseem Mehra   +3 more
doaj   +1 more source

Adult abuse and poor prognosis in Taiwan, 2000–2015: a cohort study

open access: yesBMC Public Health, 2022
Background To investigate the risk of poor prognosis regarding schizophrenic disorders, psychotic disorders, suicide, self-inflicted injury, and mortality after adult violence from 2000 to 2015 in Taiwan. Methods This study used data from National Health
Pi-Ching Yu   +12 more
doaj   +1 more source

The relationship between depression and self-mutilation in adolescence [PDF]

open access: yes, 2001
Plan BThe importance of the relationship between depression and self-mutilation in the adolescent population is becoming more apparent. Analysis of these two variables demonstrates that they are correlated with one another in the adolescent population ...
Poppe, Robyn
core  

CLRe: A Synergistic Dual‐Engine Framework for One‐Step Retrosynthesis Prediction

open access: yesAdvanced Science, EarlyView.
CLRe uses a contrastive difficulty score to order pretrained seq2seq fine‐tuning for retrosynthesis. Reaction embeddings define the ranking score, and a cumulative easy‐to‐hard schedule expands from the easiest subset to the full training set while earlier examples remain active.
Tianhao Su   +5 more
wiley   +1 more source

A Decoy‐Receptor‐Armed Biomimetic Nanotherapeutic With Inherent Tropism for Conserved Pathogenic Macrophages for Treating Osteoarthritis and Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
A biomimetic doppelgänger nanosystem neutralizes extracellular inflammatory cytokines and silences intracellular pyroptosis, reprogramming pathogenic macrophages to attenuate both joint and spine degeneration. ABSTRACT Osteoarthritis (OA) and intervertebral disc degeneration (IVDD) are debilitating musculoskeletal disorders driven by shared ...
Fudong Li   +9 more
wiley   +1 more source

Self-inflicted epistemic injustice

open access: yes
Epistemic injustice is commonly defined as a wrong done to a person or social group in their capacity as knowers by another party. This paper seeks to draw the attention of scholars working in social epistemology to the as-yet not fully explored ...
Kotsonis, Alkis
core   +1 more source

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