Results 61 to 70 of about 366,178 (284)

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients With Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

Arthritis Care &Research, EarlyView.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; ClinicalTrials.gov identifier ...
Hermine I. Brunner, Jordi Antón, Inmaculada Calvo‐Penadés, Richard Dimelow, Gerd Horneff, Sylvia Kamphuis, Rebecca Marino, Andre van Maurik, Kirsten Minden, Masaaki Mori, Josephine Ocran‐Appiah, Christel Wilkinson, Yuichi Yamasaki, Deepak Assudani, for the Pediatric Rheumatology Collaborative Study Group (PRCSG) and Paediatric Rheumatology International Trials Organisation (PRINTO) Network investigators   +14 more
wiley   +1 more source

Acceleration with Self-Injection for an All-Optical Radiation Source at LNF

, 2012
We discuss a new compact gamma-ray source aiming at high spectral density, up to two orders of magnitude higher than currently available bremsstrahlung sources, and conceptually similar to Compton Sources based on conventional linear accelerators.
Anania, M. P., Gatti, G., Giulietti, D., Gizzi, L. A., Grittani, G., Kando, M., Krus, M., Labate, L., Levato, T., Oishi, Y., Rossi, F.   +10 more
core   +1 more source

Energy boost in laser wakefield accelerators using sharp density transitions [PDF]

, 2015
The energy gain in laser wakefield accelerators is limited by dephasing between the driving laser pulse and the highly relativistic electrons in its wake.
Döpp, A., Guillaume, E., Lifschitz, A., Malka, V., Phuoc, K. Ta, Thaury, C.   +5 more
core   +3 more sources

Planar Solid‐State Nanopores Toward Scalable Nanofluidic Integration Based on CMOS Technology

Advanced Engineering Materials, EarlyView.
We present a scalable silicon‐based fabrication strategy for planar solid‐state nanopores to enable their integration with complex nanofluidic systems. Prototype devices demonstrate normal voltage‐current characteristics, good noise performance, and appreciable streaming currents. Our CMOS‐compatible fabrication process offers precise geometric control
Ngan Hoang Pham, Chenyu Wen, Mohammad Hadi Khaksaran, Won‐Yong Lee, Javier Cruz, Klas Hjort, Dongping Wu, Shi‐Li Zhang   +7 more
wiley   +1 more source

A complementary compact laser based neutron source

, 2018
Several experiments of neutron generation using high intensity laser sources, with a power exceeding 10^19W/cm^2 via TNSA (Target Normal Sheath Acceleration) or other similar methods, have been performed in the past years in different laboratories ...
A. Cianchi, Anderson, Bedogni, C. Andreani, Clark, Clayton, Esirkepov, Faure, Fuchs, G. Festa, Gaillard, Green, Haberberger, Hatchett, Henig, Kar, Koning, Ledingham, Leemans, Leemans, Litos, Lu, Muggli, O. Sans-Planell, Pomerantz, R. Bedogni, R. Senesi, Roth, Walker, Yang, Yin, Zeil   +31 more
core   +1 more source

Tuning the Dielectric Properties of Individual Clay Nanosheets by Interlayer Composition: Toward Nano‐Electret Materials

Advanced Functional Materials, EarlyView.
The dielectric properties of clays are studied on the level of individual monolayers and functional double stacks. The material breakdown characteristics and charge storage performance are analyzed. For illustration, a defined charge pattern representing a cuneiform character is produced, written into a microscopic clay tile, referencing the origins of
Sebastian Gödrich, Paul Markus, Matthias Stöter, Bernhard Biersack, Rainer Schobert, Josef Breu, Georg Papastavrou   +6 more
wiley   +1 more source

Subcutaneous formulation of belimumab in treatment of systemic lupus erythematosus: a critical review with focus on safety and satisfaction

Patient Preference and Adherence, 2018
Hamdy MA Ahmed,1–3 Samar Abohamad,2 Mohanad Elfishawi,4 Mohamed Tharwat Hegazy,2 Kadambari Vijaykumar1,5 1Internal Medicine Department, Rochester General Hospital, Rochester, NY, USA; 2Rheumatology and Clinical Immunology Unit, Internal Medicine ...
Ahmed HMA, Abohamad S, Elfishawi M, Hegazy MT, Vijaykumar K   +4 more
doaj  

Self-injected contraceptives: does the investment reflect women’s preferences?

BMJ Global Health, 2022
Subcutaneous depot medroxyprogesterone acetate (DMPA-SC) is an innovative contraceptive method aimed at meeting women’s unique circumstances and needs, largely due to its ability to be self-injected.
Sophia Magalona, Pierre Akilimali, Philip Anglewicz, Peter Gichangi, Elizabeth Omoluabi, Funmilola OlaOlorun, Georges Guiella, Shannon N. Wood, Linnea A. Zimmerman   +8 more
doaj   +1 more source

Selective and Precise Editing of Digital Polymers Through Parallel or Series Toehold‐Mediated Strand Displacement

Advanced Functional Materials, EarlyView.
A sequence‐encoded supramolecular construct containing two accessible toeholds is developed herein for enabling multiple editing operations. By introducing specific input strands, it is possible to selectively erase or rewrite digital content through parallel or series toehold‐mediated strand displacement (PTMSD or STMSD).
Jakub Ossowski, Cyril Antheaume, Jean‐François Lutz, Maria Nerantzaki   +3 more
wiley   +1 more source

Tuning the electron energy by controlling the density perturbation position in laser plasma accelerators

, 2012
A density perturbation produced in an underdense plasma was used to improve the quality of electron bunches produced in the laser-plasma wakefield acceleration scheme.
Bulanov S. V., C. Thaury, G. Lambert, K. T. Phuoc, M. Bloom, P. Brijesh, S. Corde, S. Kneip, S. P. D. Mangles, V. Malka   +9 more
core   +3 more sources