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A 3D In Vitro Model of the Human Hepatobiliary Junction
Advanced Science, EarlyView.A 3D human organoid platform reconstructs the hepatobiliary junction between primary adult hepatocytes and intrahepatic cholangiocytes. These adult hepatobiliary organoids (aHBOs) support directional bile transport from canaliculi to ductule‐like structures, enable quantitative imaging of junction dynamics, and reveal cell‐type‐specific vulnerabilities
Ashley D. Westerfield +13 more
wiley +1 more source
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2011
Emerson first described self-injurious behavior in 1913 when he posited that cutting was a symbolic substitution for masturbation. Since that early reference to the behavior, categorization models, assessment procedures, and treatment modalities have evolved. However, the research in this area is still in its infancy.
Stefan C. Dombrowski +2 more
+4 more sources
Emerson first described self-injurious behavior in 1913 when he posited that cutting was a symbolic substitution for masturbation. Since that early reference to the behavior, categorization models, assessment procedures, and treatment modalities have evolved. However, the research in this area is still in its infancy.
Stefan C. Dombrowski +2 more
+4 more sources
2019
Self-injurious behavior or SIB is a common problem among persons with intellectual disabilities. SIB can cause severe tissue damage and physical injury, interfere with educational and social development, and serve as a stressor for caregivers. As such, a thorough understanding of SIB, including assessment and treatment, is crucial for clinicians who ...
Mindy Scheithauer +3 more
openaire +1 more source
Self-injurious behavior or SIB is a common problem among persons with intellectual disabilities. SIB can cause severe tissue damage and physical injury, interfere with educational and social development, and serve as a stressor for caregivers. As such, a thorough understanding of SIB, including assessment and treatment, is crucial for clinicians who ...
Mindy Scheithauer +3 more
openaire +1 more source
Neuroscience and biobehavioral reviews, 2017
Self-injurious behavior (SIB) is a relatively common behavior in individuals with intellectual disabilities (ID). Severe SIB can be devastating and potentially life-threatening. There is increasing attention for somatic substrates of behavior in genetic syndromes, and growing evidence of an association between pain and discomfort with SIB in people ...
Huisman, Sylvia +9 more
openaire +3 more sources
Self-injurious behavior (SIB) is a relatively common behavior in individuals with intellectual disabilities (ID). Severe SIB can be devastating and potentially life-threatening. There is increasing attention for somatic substrates of behavior in genetic syndromes, and growing evidence of an association between pain and discomfort with SIB in people ...
Huisman, Sylvia +9 more
openaire +3 more sources
2006
Self-injurious behavior (SIB) viewed as a general area of pathology (e.g., McAllister, 2003) has been associated with obvious significant danger and persistence (Emerson et al. 2001), uncertain etiology (Pooley, Houston, Hawton & Harrison, 2003), and controversy in its treatments (Boyce, Carter, Penrose-Wall, Wilhelm, & Goldney, 2003; Linscheid ...
W. Larry Williams, Michele Wallace
openaire +1 more source
Self-injurious behavior (SIB) viewed as a general area of pathology (e.g., McAllister, 2003) has been associated with obvious significant danger and persistence (Emerson et al. 2001), uncertain etiology (Pooley, Houston, Hawton & Harrison, 2003), and controversy in its treatments (Boyce, Carter, Penrose-Wall, Wilhelm, & Goldney, 2003; Linscheid ...
W. Larry Williams, Michele Wallace
openaire +1 more source
2017
Self-injurious behaviors represent a heterogeneous group of behaviors that affect the individual negatively either in a physiological, physical, and/or emotional manner. Many children who have survived a traumatic event engage in nonsuicidal self-injury (NSSI) as a diversely expressed, maladaptive coping mechanism that has been associated with a ...
Victor G. Carrión +2 more
openaire +1 more source
Self-injurious behaviors represent a heterogeneous group of behaviors that affect the individual negatively either in a physiological, physical, and/or emotional manner. Many children who have survived a traumatic event engage in nonsuicidal self-injury (NSSI) as a diversely expressed, maladaptive coping mechanism that has been associated with a ...
Victor G. Carrión +2 more
openaire +1 more source
Behavior Modification, 1978
Over 60 published studies of treatment for self-injurious behavior were analyzed. The analysis involved 17 methodological factors which were considered important inclusions in research and reports in this area. Some of the factors evaluated were: quality of subject descriptions, inclusion or omission of reliability data, generalization information ...
Willard L. Johnson, Alfred A. Baumeister
openaire +1 more source
Over 60 published studies of treatment for self-injurious behavior were analyzed. The analysis involved 17 methodological factors which were considered important inclusions in research and reports in this area. Some of the factors evaluated were: quality of subject descriptions, inclusion or omission of reliability data, generalization information ...
Willard L. Johnson, Alfred A. Baumeister
openaire +1 more source