Results 81 to 90 of about 9,651,619 (292)
Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk
Molecular Oncology, EarlyView.Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley +1 more source
Nsukka Journal of Religion and Cultural Studies, 2023 Politics is about people and how they manage their affairs within a given society. Every society is a reflection of its political experiences and institutions.
Anthony Udoka Ezebuiro, Emeka Simon Ejim
doaj
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
, 2020 Reducing economic inequality and combatting climate change are two strongly supported policy goals, but they will require significant public investments.
Klaus Armingeon (839413) +1 more
core +1 more source
Education Policy Analysis Archives, 2017 Mindful of the withering of high-stakes accountability and disappointing data from pay for performance evaluations in the US, we ask why management by extrinsic incentives and organizational goal setting may have been far less powerful than designers of ...
Rick Mintrop, Miguel Ordenes
doaj +1 more source
The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer
Molecular Oncology, EarlyView.Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad +2 more
wiley +1 more source
Gratitude, Self-Interest, and Love [PDF]
Philosophia, 2014 Gratitude is usually conceived as a uniquely appropriate response to goodwill. A grateful person is bound to reward an act of goodwill in some appropriately proportionate way. I argue that goodwill, when interpreted as love, should require no reward. Consequently, the idea of gratitude as a proportionate response to love is not intelligible.
openaire +3 more sources
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
FEBS Open Bio, EarlyView.Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
MODEL TRAINING ACTIVITY OF DAILY LIVING TERHADAP KEMANDIRIAN SELF CARE PADA PENDERITA SPINAL CORD INJURY [PDF]
, 2015 : training activity of daily living, sufficiency self care, KSCE. The aims of this research is toknow the influence of the Activity of Daily Living training (activities in bed, transfer, locomotion,toileting, dressing, hygiene, and self feeding ...
Nurhidayah, Ninik, Prasaja, Prasaja
core
, 2018 Drawing on social cognitive perspectives, the present study examined an integrative model of the interplay among math self-efficacy, interests, aspirations, and achievement among early and middle adolescents.
Harsha N. Perera +7 more
core +1 more source