Results 41 to 50 of about 242,283 (264)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

A Low-Power Active Self-Interference Cancellation Technique for SAW-Less FDD and Full-Duplex Receivers

Journal of Low Power Electronics and Applications, 2017
An active self-interference (SI) cancellation technique for SAW-less receiver linearity improvement is proposed. The active canceler combines programmable gain and phase in a single stage and is co-designed with a highly-linear LNA, achieving low noise ...
Saheed Tijani, Danilo Manstretta
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Single-Shot Fringe Projection Profilometry Based on LC-SLM Modulation and Polarization Multiplexing

Photonics
Fringe projection profilometry (FPP) is extensively utilized for the 3D measurement of various specimens. However, traditional FPP typically requires at least three phase-shifted fringe patterns to achieve a high-quality phase map.
Long Shu, Junxiang Li, Yijun Du, Chen Fan, Zirui Hu, Huan Chen, Hong Zhao, Zixin Zhao   +7 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Throughput Improvement in Cellular Networks via Full-Duplex Based Device-to-Device Communications

IEEE Access, 2016
In this paper, throughput improvement of device-to-device (D2D)-aided underlaying cellular networks is analyzed. The D2D devices are assumed to be capable of operating at the full duplex (FD) mode to enable the concurrent transmission and reception with ...
Xiaomeng Chai, Tong Liu, Chengwen Xing, Hailin Xiao, Zhongshan Zhang   +4 more
doaj   +1 more source

Detection of GPS C/A Code Self-Interference: Monitor Overview and Applicability

Navigation, 2023
Self-interference can cause large errors of up to tens of meters on the GPS C/A code pseudorange measurement. Although the probability of an occurrence of large self-interference errors is small, to enable the use of C/A code phase measurements in high ...
Jessica Belzer, Frank van Graas
doaj   +1 more source