Results 61 to 70 of about 1,436,608 (272)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Self Course: Lessons Learned from Students’ Weekly Questions
Behavioral Sciences, 2023 In this paper, I tentatively answer 50 questions sampled from a pool of over 10,000 weekly questions formulated by students in a course entitled “The Self”.
Alain Morin
doaj +1 more source
Contrastivism and anti-individualism: a response to Aikin and Dabay [PDF]
, 2014 In this paper I clarify my argument for the claim that contrastive self-knowledge entails anti ...
Sawyer, Sarah
core
Failures of rationality and self-knowledge in addiction [PDF]
, 2017 The focus of this chapter is the account of akrasia in alcoholism suggested by the Alcoholics Anonymous literature. The chapter begins by sketching out this account of akrasia. It then goes on to raise a number of questions about this account.
Crowther, Thomas
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Высшее образование в России, 2019 Faith and understanding are in a complex relationship with each other; they are living in their own way in the depths of every developed human consciousness.
A. E. Razumov
doaj +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
Molecular Oncology, EarlyView.PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
Russell on Introspection and Self-Knowledge [PDF]
, 2018 This chapter examines Bertrand Russell's developing views--roughly from 1911 to 1918--on the nature of introspective knowledge and subjects' most basic knowledge of themselves as themselves.
Wishon, Donovan
core
Dretske on Self-Knowledge and Contrastive Focus: How to Understand Dretske’s Theory, and Why It Matters [PDF]
, 2017 Dretske’s theory of self-knowledge is interesting but peculiar and can seem implausible. He denies that we can know by introspection that we have thoughts, feelings, and experiences.
Roche, Michael, Roche, William
core +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source