Results 121 to 130 of about 3,992,332 (307)

Self-reported Work Disability in the US and The Netherlands [PDF]

Self-reported work disability is analyzed in the US and The Netherlands. The raw data show that Dutch respondents much more often report that they have a work limiting health problem than respondents in the US. The difference remains when controlling for
Arthur van Soest, James P. Smith, Arie Kapteyn   +2 more
core  

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Longitudinal association between handgrip strength and depressive symptoms in middle-aged and older Chinese adults: mediating role of functional limitation

Frontiers in Public Health
BackgroundThe relationship between handgrip strength (HGS) at baseline and subsequent depressive symptoms among middle-aged and older Chinese adults remains highly uncertain.
Yanchang Liu, Junling Cui, Xin Luo, Zhuzhu Wang, Ziyi Shen, Yan Fang, Chengcheng Li, Jingfang Hong   +7 more
doaj   +1 more source

Long‐Term Follow‐Up of Chemotherapy‐Associated Biological Aging in Women With Early Breast Cancer

Aging and Cancer, EarlyView.
Women threated with adjuvant chemotherapy for early breast cancer have sustained long‐term increase in p16INK4a,, a robust marker of cell senescence, suggesting a chemotherapy‐associated age acceleration. p16INK4a as well as other biomarkers may identify patients at greatest risk for senescence‐related diseases of aging.
Hyman B. Muss, Alexis C. Wardell, Allison M. Deal, Kirsten A. Nyrop, Allison Ross, Yara G. Abdou, Jeffrey D. Aldrich, Lisa A. Cary, E. Claire Dees, Katherine E. Reeder‐Hayes, Emily M. Ray, Natalia Mitin, Denis Tsygankov   +12 more
wiley   +1 more source

Castoriadis’ Concept of Institution and Democracy

Nordicum-Mediterraneum, 2008
In this article I discuss the relation between institution and democracy in Castoriadis’ philosophy. The paper proposes an outline of the development of Castoriadis’ political philosophy with focus on institutionalization, imagination and self-limitation
Dahl Rendtorff, Jacob
doaj  

Work limitations, business maintenance, and demoralization in self-employed individuals with cardiac diseases

BMC Research Notes
Objective Self-employed individuals managing chronic illnesses such as cardiac diseases are at heightened risk for psychological distress. This study aimed to examine the relationship between work limitations resulting from cardiac disease and ...
Wafaa Sowan, Sabaa Masarwe
doaj   +1 more source

Self-limited [PDF]

Nature, 2016
openaire   +1 more source

Who's on first? : causal ordering of ademic self-concept, motivational goals, and achievement

, 2004
Investigating causal relations between self-concept and motivational goals represents a leading edge in self-concept research. The objective of the study was to determine the nature and extent of causal relations between students’ academic self-concept ...
Dowson, Martin, Barker, Katrina L., McInerney, Dennis M.   +2 more
core  

Intelligent Tutoring Systems for Adult Learning in STEM Disciplines

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley   +1 more source

Artificial Intelligence and Mental Well‐Being in Adult Education: Implications for Practice and Professional Responsibility

New Directions for Adult and Continuing Education, EarlyView.
ABSTRACT Mental well‐being is central to adult learner success, yet many adult education institutions lack capacity to provide timely and accessible support. This article examines how artificial intelligence (AI) can strengthen mental health–adjacent supports in adult and continuing higher education, with attention to professional practice and ...
Adam L. McClain, Thomas Wade
wiley   +1 more source