Results 111 to 120 of about 5,587,649 (306)

Self Study

, 2013
Department of Political Science Self Study Report for Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ReviewDepartment of Political Science Self Study Report Academic Program ...
Academic Program Review, APR, Political Science, Self Study, Department of Political Science, Self Study Report   +2 more
core  

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Pollen-limitation-Table-2

, 2018
Pollen limitation for arrays of Campanula americana from high and medium autogamy populations in placed in sun and shade ...
Koski, Matthew, Anne Rowe (5028551), Lia Leibman (5028548), Rowe, Anne, Matthew Koski (3271299), Leibman, Lia, Galloway, Laura, Laura Galloway (3192098)   +7 more
core   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Mechanisms of possible self-limitation in the invasive Asian shore crab Hemigrapsus sanguineus. [PDF]

Sci Rep, 2020
Griffen BD, Bailey J, Carver J, Vernier A, DiNuzzo ER, Anderson L, Meidell M, Potter B.   +7 more
europepmc   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Work limitations, business maintenance, and demoralization in self-employed individuals with cardiac diseases

BMC Research Notes
Objective Self-employed individuals managing chronic illnesses such as cardiac diseases are at heightened risk for psychological distress. This study aimed to examine the relationship between work limitations resulting from cardiac disease and ...
Wafaa Sowan, Sabaa Masarwe
doaj   +1 more source

Self-concepts of primary students with mild intellectual disabilities : issues of measurement and educational placement

, 2000
The educational placement of students with mild intellectual disabilities remains controversial. Arguments for educational placement are often based upon the anticipated impact upon self-concept.
Tracey, Danielle K. (R13635), Marsh, Herbert W. (R8137)   +1 more
core  

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source