Results 71 to 80 of about 5,587,649 (306)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Pollen limitation and dependence on cross-pollination in borage (Borago officinalis L.) in the Pampas region of Argentina

Journal of Pollination Ecology
Borago officinalis L. is an insect-pollinated crop valued for its seed oil. While described as self-compatible, the extent to which its reproductive success depends on pollinator-mediated cross-pollination and whether it experiences pollen limitation in
Martina Matos, Mariano Devoto
doaj   +1 more source

Self-beliefs and bullying : unravelling the relation between bullying, being bullied and self-concept for upper elementary school aged children

, 2006
Previous examinations of relations between bullying, victimisation, and self-concept have been flawed by erroneous research practices such as the un-attenuated use of dichotomous variables to measure relationships between continuous variables (Finger ...
Finger, Linda R., Dowson, Martin, Craven, Rhonda   +2 more
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Functional limitation and cardiometabolic health: a cross-sectional exploration in adults aged 30 and older in rural Punjab, India

BMC Public Health
Background We investigated the distribution of cardiometabolic health outcomes in people with and without functional limitation in rural India. Method In a cross-sectional, population-based sample of 3,023 adults aged ≥ 30 years in a rural setting in ...
Dewan Muhammad Shoaib, Hanspria Sharma, Devraj Jindal, Priti Gupta, Prashant Jarhyan, Sailesh Mohan, Nikhil Tandon, Shivani A. Patel   +7 more
doaj   +1 more source

UNSUSPECTED FACTORS IN ‘SELF‐LIMITING’ AILMENTS

International Journal of Clinical Practice, 1992
SUMMARYAn unsuspected subtotally perforated eardrum treated with wax softening drops shows how clinical findings do not always correlate with symptoms or history. Attention is drawn to the dilemma posed by delegating matters such as diagnosis and prescribing which have been considered to be purely in the medical sphere.
J D, Bennett, H W, McFarlane
openaire   +2 more sources

The relation of self-concept to desirable educational outcomes

, 2006
Reviewers (Byrne, 1996a, 1996b; Hattie, 1992; Marsh, Byrne, & Shavelson, 1988; Marsh & Craven, 1997; Craven, Marsh, & Burnett, 2003) consider that self-concept is multifaceted and espouse that self-concept cannot be adequately understood if its ...
Craven, Rhonda, Munns, Geoff, Ha, My Trinh, Martin, Andrew J.   +3 more
core  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Thermodynamic Size Control in Curvature-Frustrated Tubules: Self-Limitation with Open Boundaries. [PDF]

ACS Nano, 2022
Tyukodi B, Mohajerani F, Hall DM, Grason GM, Hagan MF.   +4 more
europepmc   +1 more source