Results 61 to 70 of about 16,736,918 (289)

Longitudinal Investigation of Older Adults' Ability to Self‐Manage Complex Drug Regimens

Journal of the American Geriatrics Society, 2019
OBJECTIVES We sought to investigate older patients' ability to correctly and efficiently dose multidrug regimens over nearly a decade and to explore factors predicting declines in medication self‐management. DESIGN Longitudinal cohort ...
Stacy Cooper, Bailey, Lauren A, Opsasnick, Laura M, Curtis, Alex D, Federman, Julia Y, Benavente, Rachel, O'Conor, Michael S, Wolf   +6 more
openaire   +3 more sources

Motivational Interviewing to Promote Self-Management

, 2017
Motivational interviewing is an empathetic approach for facilitating behavior change. Clinicians can use this approach to support individuals with chronic health conditions to identify opportunities for behavior change and develop a plan for working ...
Greenfield, David, Martz, Erin, Hogden, Anne, Phillips, Rebecca, Rebecca Phillips, Anne Hogden, David Greenfield   +6 more
core   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Construction and effect evaluation of extended integrative nursing model for patients with diabetic retinopathy (糖尿病视网膜病变患者中西医延续护理模式的构建及效果评价)

中西医结合护理
Objective To explore the construction and effect of the extended integrative nursing model for patients with diabetic retinopathy (DR). Methods A total of 100 DR Patients treated in our hospital from August 2024 to February 2025 were selected and ...
WANG Qiao (王俏), LIN Zihan (林姿含), LI Jing (李静)   +2 more
doaj   +1 more source

What we know about the purpose, theoretical foundation, scope and dimensionality of existing self-management measurement tools: A scoping review

, 2018
Contains fulltext : 190995.pdf (Publisher’s version ) (Closed access)OBJECTIVES: To identify self-report, self-management measures for adults with chronic conditions, and describe their purpose, theoretical foundation, dimensionality ...
van Gaal, Betsie G.I., Warner, G., Betsie G.I. van Gaal, Fracini, A., Audulv, A., Kephart, G., Alizadeh, N., Kephart, George, Tanya L. Packer, Fracini, America, Packer, Tanya L., Audulv, Åsa,, Neda Alizadeh, Alizadeh, Neda, Gaal, B. van, Åsa Audulv, Grace Warner, George Kephart, Warner, Grace, Packer, T.L., America Fracini, Alizadeh, Neda,, Packer, Tanya,, Kephart, George,, Fracini, America,, van Gaal, Betsie G I,, Warner, Grace,   +26 more
core   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Qualitative analysis of out-of-hospital self-management capabilities and ongoing care needs in patients with gynecological malignancies and venous thromboembolism

Annals of Medicine
Background Postoperative patients with gynecological malignant tumors are prone to venous thromboembolism (VTE) due to hypercoagulability and limited mobility, and lack of professional guidance after discharge, further increasing the risk of VTE ...
Tian-Hua Li, Yan-Wei Wang, Jing-Xuan Feng, Ning Sun, Ya-Jing Bian, Jun-Ying Ma, Lai-You Li   +6 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

Self-Management Ability of Patients with PICC Catheter and Its Influencing Factors

, 2022
Abstract Objective: Explore the self-management ability of patients with PICC catheter and its influencing factors, so as to provide basis for improving self-management ability. Methods: A total of 240 patients with PICC catheter in a Grade-A hospital are investigated by convenient sampling.
Tao-Hsin Tung, liguang Chen, Gang Wang, Xinxin Zhang, Weijiao Xu, Xiaodan Chen, Ying Xu   +6 more
openaire   +1 more source