Results 51 to 60 of about 157,060 (311)

Progress on self-mixing sensors for in-situ displacement measurement [PDF]

2013 IEEE 11th International Workshop of Electronics, Control, Measurement, Signals and their application to Mechatronics, 2013
This document presents a survey on reported devices exploiting the emerging technology of self-mixing interferometry for non-contact displacement reconstruction. Nowadays, there is a broad diversity of signal processing methods over self-mixing devices, making difficult to decide which one would satisfy a given application domain.
Luna Arriaga, Antonio, Bosch, Thierry, Bony, Francis   +2 more
openaire   +2 more sources

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Characteristics of turbulent mixing at late stage of the Richtmyer-Meshkov instability

AIP Advances, 2017
We present a model for the mixing width, h, at self-similar stage of the Richtmyer-Meshkov instability (RMI). The derivation of the model is based on the formula of the growth rate of mixing width [Gao et al., Phys.
Fujie Gao, Yousheng Zhang, Zhiwei He, Li Li, Baolin Tian   +4 more
doaj   +1 more source

Portable Low-Power Fully Digital Radio-Frequency Direct-Transceiving See-Through-Wall Radar

IEEE Access, 2020
A see-through-wall (STW) radar system based on a direct digital-logic radio-frequency (RF) pulse generator and an equivalent-time direct RF-sampling receiver chipset is proposed. Both the transmitter and the receiver of the radar system are both operated
Ping Li, Feng Zhou, Peng Luo, Maliang Liu   +3 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Self-mixing interferometry and its applications

SPIE Proceedings, 2016
This paper reviews the self-mixing interference (SMI) in terms of its operation principle, the features of SMI signals and its configuration. SMI refers to a phenomenon that occurs when a small fraction of the light emitted by a laser is backscattered or reflected by an external target and re-enters the laser active cavity, thus leading to the ...
Yanguang Yu, Yuanlong Fan, Bin Liu
openaire   +2 more sources

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Numerical Diffusion and Turbulent Mixing in Convective Self‐Aggregation

Journal of Advances in Modeling Earth Systems
Convective Self‐Aggregation (CSA) is a common feature of idealized numerical simulations of the tropical atmosphere in Radiative‐Convective Equilibrium (RCE).
L. Silvestri, M. Saraceni, P. Bongioannini Cerlini   +2 more
doaj   +1 more source

Laser Self-Mixing Grating Interferometer for MEMS Accelerometer Testing

IEEE Photonics Journal, 2018
A simple and robust testing system based on a laser self-mixing grating interferometer (SMGI) is proposed to determine the sensitivity of accelerometers. Self-mixing grating interference occurs when the light emitted from a laser diode is incident onto a
Dongmei Guo, Haiqing Jiang, Liheng Shi, Ming Wang   +3 more
doaj   +1 more source