Results 71 to 80 of about 867,953 (285)

Inferring collective dynamical states from widely unobserved systems

open access: yesNature Communications, 2018
From infectious diseases to brain activity, complex systems can be approximated using autoregressive models. Here, the authors show that incomplete sampling can bias estimates of the stability of such systems, and introduce a novel, unbiased metric for ...
Jens Wilting, Viola Priesemann
doaj   +1 more source

Anticipating the impact of COVID19 and comorbidities on the South African healthcare system by agent-based simulations

open access: yesScientific Reports, 2021
Tuberculosis (TB) is the 10th leading cause of death worldwide, and since 2007 it has been the main cause of death from a single infectious agent, ranking above HIV/AIDS. The current COVID-19 is a pandemic which caused many deaths around the world.
Jan Christian Schlüter   +5 more
doaj   +1 more source

Self Organization and Self Avoiding Limit Cycles

open access: yes, 2014
A simple periodically driven system displaying rich behavior is introduced and studied. The system self-organizes into a mosaic of static ordered regions with three possible patterns, which are threaded by one-dimensional paths on which a small number of
Hexner, Daniel, Levine, Dov
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Predicting effectiveness of countermeasures during the COVID-19 outbreak in South Africa using agent-based simulation

open access: yesHumanities & Social Sciences Communications, 2021
COVID-19 has spread rapidly around the globe. While there has been a slow down of the spread in some countries, e.g., in China, the African continent is still at the beginning of a potentially wide spread of the virus.
Moritz Kersting   +4 more
doaj   +1 more source

Self-organization of (001) cubic crystal surfaces

open access: yes, 2001
Self-organization on crystal surface is studied as a two dimensional spinodal decomposition in presence of a surface stress. The elastic Green function is calculated for a $(001)$ cubic crystal surface taking into account the crystal anisotropy ...
A. G. Khachaturyan   +22 more
core   +2 more sources

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

open access: yesFEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

Why human connection is the true metric of research success

open access: yesFEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan   +3 more
wiley   +1 more source

Motility-induced mixing transition in exponentially growing multicellular spheroids

open access: yesCommunications Physics
Growth drives cellular dynamics in dense aggregates, including bacterial colonies, developing tissues, and tumors. However, its effects on other relevant activities have not received sufficient attention.
Torben Sunkel   +2 more
doaj   +1 more source

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