Results 81 to 90 of about 8,265,161 (304)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Self-organization of (001) cubic crystal surfaces

, 2001
Self-organization on crystal surface is studied as a two dimensional spinodal decomposition in presence of a surface stress. The elastic Green function is calculated for a $(001)$ cubic crystal surface taking into account the crystal anisotropy ...
A. G. Khachaturyan, A. Karma, A. Zangwill, C. Wagner, F.M. Leibsle, H. Ellmer, H.E. Cook, I.M. Lifshitz, J. Tersoff, J. Villain, K. Kassner, Klaus Kern, Kwok-On Ng, L.Q. Chen, Laurent Proville, M. Pinczolits, M. Sotto, O.L. Alerhand, S. Narasimhan, S. Song, T.W. Fishlock, V. Repain, V.I. Marchenko   +22 more
core   +2 more sources

Behavioral self-organization underlies the resilience of a coastal ecosystem

Proceedings of the National Academy of Sciences of the United States of America, 2017
Significance Theoretical models suggest that spatial self-organization enhances the resistance of ecosystems to disturbance. However, experiments investigating this important prediction are lacking.
H. de Paoli, T. van der Heide, Aniek van den Berg, B. Silliman, P. Herman, J. van de Koppel   +5 more
semanticscholar   +1 more source

Self-organization in populations of competing agents

, 2000
A population of heterogenous agents compeeting through a minority rule is investigated. Agents which frequently loose are selected for evolution by changing their strategies.
Vazquez, Alexei
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

Motility-induced mixing transition in exponentially growing multicellular spheroids

Communications Physics
Growth drives cellular dynamics in dense aggregates, including bacterial colonies, developing tissues, and tumors. However, its effects on other relevant activities have not received sufficient attention.
Torben Sunkel, Lukas Hupe, Philip Bittihn   +2 more
doaj   +1 more source

Optimal navigation of microswimmers in complex and noisy environments

New Journal of Physics, 2022
We design new navigation strategies for travel time optimization of microscopic self-propelled particles in complex and noisy environments. In contrast to strategies relying on the results of optimal control theory or machine learning approaches ...
Lorenzo Piro, Benoît Mahault, Ramin Golestanian   +2 more
doaj   +1 more source

Self-organization without conservation: Are neuronal avalanches generically critical?

, 2010
Recent experiments on cortical neural networks have revealed the existence of well-defined avalanches of electrical activity. Such avalanches have been claimed to be generically scale-invariant -- i.e.
Bak P, Beggs J M, Bonachela J A, Cardy J L, Dayan P, Freeman W J, Gerstner W, Grinstein G McKane A, Harris T E, Jensen H J, Joaquín J Torres, Juan A Bonachela, Levina A, Miguel A Muñoz, Priesemann V, Pruessner G, Sebastiano de Franciscis   +16 more
core   +1 more source