Results 61 to 70 of about 30,395 (263)
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Self-organizing Maps and Ancient Documents [PDF]
, 2004 This paper presents how Self-Organizing Maps and especially Kohonen maps can be applied to digital images of ancient collections in the perspective of valorization and diffusion. As an illustration, a scheme of transparency reduction of the digitized Gutenberg Bible is presented. In this two steps method, the Kohonen map is trained to generate a set of
Smigiel, Eddie +2 more
openaire +2 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
A NEW RECOGNITION TECHNIQUE NAMED SOMP BASED ON PALMPRINT USING NEURAL NETWORK BASED SELF ORGANIZING MAPS [PDF]
ICTACT Journal on Image and Video Processing, 2012 The word biometrics refers to the use of physiological or biological characteristics of human to recognize and verify the identity of an individual.
A. S. Raja, V. Joseph Raj
doaj
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Discerning protein pools by selective staining with self‐labeling tags
FEBS Letters, EarlyView.Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley +1 more source
Saviorganizuojančių neuroninių tinklų sistemų lyginamoji analizė
Informacijos Mokslai, 2009 Straipsnyje nagrinėjamos ir lyginamos tarpusavyje trys saviorganizuojančių neuroninių tinklų (SOM) sistemos: NeNet, SOM-Toolbox ir Databionic ESOM. Pagrindinis šių sistemų tikslas yra suskirstyti duomenis į klasterius pagal jų panašumą, pateikti juos SOM
Pavel Stefanovič, Olga Kurasova
doaj +1 more source
Winner-Relaxing Self-Organizing Maps [PDF]
Neural Computation, 2005 A new family of self-organizing maps, the winner-relaxing Kohonen algorithm, is introduced as a generalization of a variant given by Kohonen in 1991. The magnification behavior is calculated analytically. For the original variant, a magnification exponent of 4/7 is derived; the generalized version allows steering the magnification in the wide range ...
openaire +2 more sources