Results 71 to 80 of about 397,121 (285)
Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting
Molecular Oncology, EarlyView.CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia +9 more
wiley +1 more source
Book publishing in Vyatka region in the early XX century
Библиосфера, 2017 The Russian government in the field of extracurricular education in the early XX century persuded certain goals: preserving the state foundations inviolability, spreading the Orthodoxy tenets, raising the people cultural level.
Yu. V. Pershina
doaj +1 more source
Strength through diversity: how cancers thrive when clones cooperate
Molecular Oncology, EarlyView.Intratumor heterogeneity can offer direct benefits to the tumor through cooperation between different clones. In this review, Kuiken et al. discuss existing evidence for clonal cooperativity to identify overarching principles, and highlight how novel technological developments could address remaining open questions.
Marije C. Kuiken +3 more
wiley +1 more source
INDIE BOOK CORNER SEBAGAI MEDIA SELF-PUBLISHING KAJIAN SOSIOLOGI PRODUKSI DAN DISTRIBUSI [PDF]
, 2017 Latifah, Annas Chairunnisa. 2017. "Indie Book Corner as Self-Publishing Media Study of Production and Distribution Sociology" Thesis (S1) Indonesia Literature. Fakultas Ilmu Budaya Universitas Diponegoro. Adviser I Dr. Redyanto Noor, M.Hum.
Annas Chairunnisa, Latifah
core
Next‐generation proteomics improves lung cancer risk prediction
Molecular Oncology, EarlyView.This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj +4 more
wiley +1 more source
Zeitschrift für digitale Geisteswissenschaften, 2015 Open review projects and wikis are changing academic knowledge production, just as academic blogs and social media are influencing scholarly communication.
Thomas Ernst
doaj +1 more source
Science 3.0: Corrections to the Science 2.0 paradigm [PDF]
, 2013 The concept of Science 2.0 was introduced almost a decade ago to describe the new generation of online-based tools for researchers allowing easier data sharing, collaboration and publishing.
Teif, Vladimir B.
core +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source