Results 71 to 80 of about 571,969 (257)

Textbooks in transitional countries: Towards a methodology for comparative analysis

Knjižnica, 2004
In its first part, the paper analyses the ambiguous nature of the book as a medium: its physical production and its distribution to the end user takes place on a market basis; on the other hand, its content is predominantly consumed in a sector that was ...
Miha Kovač, Mojca Kovač Šebart
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

La plateforme d’autoédition Librinova au prisme de la reconfiguration de l’intermédiation littéraire

Tic & Société, 2019
For a little less than a decade, self-publishing platforms for fiction have come to occupy a central position in the book industry. In a context of socioeconomic and cultural changes, they reflect a reconfiguration of the auctorial space, under the ...
Sylvie BOSSER
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

Publication integrity and industry influences on the editorial process: a case study

Research Integrity and Peer Review
Scholarly publishing is facing unprecedented challenges. Journal scholarly integrity and ethics have historically focused on author conduct and conflicts of interest. We address apparent journal and editor conflicts of interest.
Evan D. Kharasch, Michael M. Todd, Jean-Francois Pittet, William L. Lanier   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Chinese university faculty’s motivation and language choice for scholarly publishing [PDF]

Ibérica, 2019
Research on scholarly publishing has focused predominantly on bi/multilingual researchers’ experiences and practices of publishing in English with scant attention paid specifically to their motivation and language choice for bi/multilingual publishing ...
Jun Lei , Tianmin Jiang
doaj   +2 more sources

Open and impactful academic publishing

Frontiers in Research Metrics and Analytics
IntroductionThe advantages of self-archiving research articles on institutional repositories or personal academic websites are numerous and relevant for society and individual researchers.
Rosaria Ciriminna, Giovanna Li Petri, Giuseppe Angellotti, Rafael Luque, Mario Pagliaro   +4 more
doaj   +1 more source