Results 41 to 50 of about 335,406 (261)

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Cross-classification between self-rated health and health status: longitudinal analyses of all-cause mortality and leading causes of death in the UK

open access: yesScientific Reports, 2022
Risk stratification is an important public health priority that is central to clinical decision making and resource allocation. The aim of this study was to examine how different combinations of self-rated and objective health status predict all-cause ...
Julian Mutz, Cathryn M. Lewis
doaj   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

Self-Rated Health: Inequalities and Potential Determinants [PDF]

open access: yesInternational Journal of Environmental Research and Public Health, 2009
Understanding social inequalities in health is of great importance; it provides the conceptual frame for investigating the social factors that affect health, together with empirical evidence for improving population health. Individual and socioeconomic data, disease related conditions and self rated health (SRH) ratings were collected from a ...
Evangelos C. Alexopoulos, Mary Geitona
openaire   +2 more sources

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Bidirectional relationship between self-rated health and the big five personality traits among Chinese adolescents: a two-wave cross-lagged study

open access: yesHumanities & Social Sciences Communications
Previous literature has focused mainly on the correlation between self-rated health and the Big Five personality traits. However, less is known about the bidirectional relationship between self-rated health and the Big Five personality traits among ...
Xiaojie Cao, Siduo Ji
doaj   +1 more source

Self-Rated Health and Adverse Events in CKD [PDF]

open access: yesClinical Journal of the American Society of Nephrology, 2014
Little is known about the utility of self-rated general health assessments in persons with moderate-to-severe CKD. This study examined the ability of a single self-rated health measure to predict all-cause mortality and kidney disease progression in a cohort of 443 patients with stages 3-4 CKD, recruited between 2005 and 2011, and followed until the ...
Cassianne, Robinson-Cohen   +6 more
openaire   +2 more sources

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Association of objective sedentary behaviour and self-rated health in English older adults

open access: yesBMC Research Notes, 2019
Objective Reducing sedentary behaviour (SB) might improve the health of older adults. However, we know little about how objectively measured SB impacts on self-rated health in older adults.
Jason J. Wilson   +5 more
doaj   +1 more source

The moderating role of neighborhood disadvantage on the link between functional limitations and self-rated health.

open access: yesPLoS ONE, 2023
BackgroundSelf-rated health is an important health outcome and determinant of health. Improvements to our understanding on self-rated health could help design plans and strategies to improve self-rated health and achieve other preferred health outcomes ...
Jeong Ha Steph Choi, Daniel H Jung
doaj   +1 more source

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