Results 71 to 80 of about 335,406 (261)

The sex difference in self-rated health among older Turkish and Moroccan migrants in the Netherlands: an exploratory study of contributing determinants

BMC Public Health
Background Although being a woman and having a migration background are strong predictors of poor self-rated health among (older) adults, research on the sex difference in self-rated health among (older) migrants remains limited.
Lena D. Sialino, H. A.H. Wijnhoven, S. H. van Oostrom, H. S.J. Picavet, M. Visser, L. A. Schaap   +5 more
doaj   +1 more source

Self-rated and changes in self-rated health as predictors of mortality

, 2005
Background: Studies from several countries have shown that self-rated health is an independent predictor of mortality. However, no empirical evidence exists for Germany so far. We investigate the effectiveness of (i) self-ratings of health by individuals and (ii) changes in self-rated health, as predictors of mortality for Germany.
Schwarze, Johannes, Andersen, Hanfried H., Anger, Silke   +2 more
openaire   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Guiding AlphaFold to predict how Munc13‐1 opens Syntaxin‐1

FEBS Open Bio, EarlyView.
The syntaxin‐1 Habc‐domain (orange), linker (pink) and SNARE motif (yellow) form a closed conformation that binds to Munc18‐1 (violet) and is opened by the Munc13‐1 MUN domain (cyan) to form the SNARE complex that triggers neurotransmitter release.
Madhurima Chattopadhyay, Junjie Xu, Josep Rizo   +2 more
wiley   +1 more source

Relationship between growth mindset and self-rated health in Chinese college teachers: sequential mediating effect of health self-efficacy and physical exercise

Frontiers in Public Health
BackgroundChinese college teachers’ health issues have become increasingly significant, making it crucial to promote their physical health. Based on self-regulation theory, this study aims to explore the relationship and underlying mechanisms between ...
Tao Yu, Change Zeng, Lidong He, Hu Ying, Jie Liu, Yuzhen Wu, Jiayuan Li, Yaxing Guo, Yanjun Chen, Xiaofu Pan   +9 more
doaj   +1 more source

The impact of sleep duration on self-rated health

Sleep Science, 2014
Purpose: To review the association between sleep duration and self-rated health. Methods: A search for original and review articles focusing on sleep duration and self-rated health was performed in PubMed.
Cristina Frange, Sandra Souza de Queiroz, Juliana Martuscelli da Silva Prado, Sergio Tufik, Marco Túlio de Mello   +4 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Aging Is a Key Driver for Adult Acute Myeloid Leukemia

Aging and Cancer, EarlyView.
Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley   +1 more source

Gender differences in predictors of self-rated health in Armenia: a population-based study of an economy in transition

International Journal for Equity in Health, 2012
Introduction Self-rated health is a widely used health outcome measure that strongly correlates with physical and mental health status and predicts mortality.
Demirchyan Anahit, Petrosyan Varduhi, Thompson Michael E   +2 more
doaj   +1 more source